Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

Bacterial infection, which is still one of the leading causes of death in humans, poses an
enormous threat to the worldwide public health system. Antibiotics are the primary …

Chalcones have various biological effects, from immune boosting to anti-cancer and anti-
diabetic. Structurally modified chalcones (SMC) are clinically relevant for diabetes and …

Diabetes mellitus (DM) is a major metabolic disorder due to hyperglycemia, which is
increasing all over the world. From the last two decades, the use of synthetic agents has …

This research emphasizes a new modeling approach by Box Behnken Design in Response
Surface Methodology (RSM) for the optimization of chalcones yield based to the elaborated …

Small organic molecules with interesting optical and electrochemical properties find
applications as organic luminescent materials. In this work, we report the synthesis of novel …

Development and discovery of new antimalarial drugs are needed to overcome the multi-
resistance of Plasmodium parasites to commercially available drugs. Modifying the …

The application of QSAR along with other in silico tools like molecular docking, and
molecular dynamics provide a lot of promise for finding new treatments for life-threatening …

In the present work, we have synthesized a new Schiff base 6-nitro-benzimidazole derivative
(3a and 3b) and were confirmed by analytical and spectroscopic methods. TiO 2 …