Epigenomic studies aim to define the location and nature of the genomic sequences that are
epigenetically modified. Much progress has been made towards whole-genome epigenetic …

Short retroposons (SINEs) are repetitive elements amplified in the genome via an RNA
intermediate, using the enzymatic machinery of autonomous retroposons (LINEs). SINEs are …

Organization of the genome into euchromatin and heterochromatin appears to be
evolutionarily conserved and relatively stable during lineage differentiation. In an effort to …

L1 retrotransposons are transposable elements and major contributors of genetic variation
in humans. Where L1 integrates into the genome can directly impact human evolution and …

Processed pseudogenes were created by reverse-transcription of mRNAs; they provide
snapshots of ancient genes existing millions of years ago in the genome. To find them in the …

SVA is a composite repetitive element named after its main components, SINE, VNTR and
Alu. We have identified 2762 SVA elements from the human genome draft sequence …

Remnants of more than 3 million transposable elements, primarily retroelements, comprise
nearly half of the human genome and have generated much speculation concerning their …

Repetitive elements are abundantly distributed in mammalian genomes. Here, we reveal a
striking association between repeat subtypes and gene function. SINE, L1, and low …

Cell-free DNA (cfDNA) in body tissues or fluids is extensively investigated in clinical
medicine and other research fields. In this article we provide a direct quantitative real-time …

Pseudogenes are important resources in evolutionary and comparative genomics because
they provide molecular records of the ancient genes that existed in the genome millions of …