Purpose We conducted a systematic literature review to summarize the current health economic evidence for whole-exome sequencing (WES) and whole-genome sequencing …
AA Witney, CA Cosgrove, A Arnold, J Hinds, NG Stoker… - BMC medicine, 2016 - Springer
Drug-resistant tuberculosis (TB) remains a major challenge to global health and to healthcare in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of …
M Su, SW Satola, TD Read - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Clinical microbiology has long relied on growing bacteria in culture to determine antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …
In order to retard the rate of development of antibacterial resistance, the causative agent must be identified as rapidly as possible, so that directed patient treatment and/or contact …
Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained declines in tuberculosis deaths in many countries during the past 50 years provide …
CRyPTIC Consortium and the 100,000 … - … England Journal of …, 2018 - Mass Medical Soc
Abstract Background The World Health Organization recommends drug-susceptibility testing of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment …
B Acharya, A Acharya, S Gautam, SP Ghimire… - Molecular biology …, 2020 - Springer
Tuberculosis (TB) is a major cause of deaths by a single infectious agent and has now been a global public health problem due to increasing numbers of drug-resistant cases. Early and …
N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and control programmes worldwide. Advances in sequencing technology have significantly …