The risks of long-term use of proton pump inhibitors: a critical review

M Jaynes, AB Kumar - Therapeutic advances in drug safety, 2019 - journals.sagepub.com
Proton pump inhibitors (PPIs) are among the most frequently prescribed medications. Their
use is likely even higher than estimated due to an increase in the number of PPIs available …

Risk factors for recurrent Clostridium difficile infection: a systematic review and meta-analysis

A Deshpande, V Pasupuleti, P Thota, C Pant… - infection control & …, 2015 - cambridge.org
OBJECTIVEAn estimated 20–30% of patients with primary Clostridium difficile infection
(CDI) develop recurrent CDI (rCDI) within 2 weeks of completion of therapy. While the actual …

[HTML][HTML] European Society of Clinical Microbiology and Infectious Diseases: 2021 update on the treatment guidance document for Clostridioides difficile infection in …

J van Prehn, E Reigadas, EH Vogelzang… - Clinical Microbiology …, 2021 - Elsevier
Abstract Scope In 2009, the European Society of Clinical Microbiology and Infectious
Diseases (ESCMID) published the first treatment guidance document for Clostridioides …

[HTML][HTML] Proton pump inhibitor use and risk for recurrent Clostridioides difficile infection: a systematic review and meta-analysis

KM D'Silva, R Mehta, M Mitchell, TC Lee… - Clinical Microbiology …, 2021 - Elsevier
Background Proton pump inhibitor (PPI) therapy is a potentially modifiable risk factor for
recurrent Clostridioides difficile infection (CDI). Citing an absence of clinical trials, many …

[HTML][HTML] Prognostic factors for severe and recurrent Clostridioides difficile infection: a systematic review

TM van Rossen, RE Ooijevaar… - Clinical Microbiology …, 2022 - Elsevier
Objectives Clostridioides difficile infection (CDI), its subsequent recurrences (rCDIs), and
severe CDI (sCDI) provide a significant burden for both patients and the healthcare system …

Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and …

T Oshima, L Wu, M Li, H Fukui, J Watari… - Journal of …, 2018 - Springer
Background Clostridium difficile infection (CDI) is a cause of increased morbidity and health
care costs among hospitalized patients. Proton pump inhibitors (PPIs) are mainly used for …

Lactobacillus rhamnosus L34 and Lactobacillus casei L39 suppress Clostridium difficile-induced IL-8 production by colonic epithelial cells

P Boonma, JK Spinler, SF Venable, J Versalovic… - BMC microbiology, 2014 - Springer
Background Clostridium difficile is the main cause of hospital-acquired diarrhea and colitis
known as C. difficile-associated disease (CDAD). With increased severity and failure of …

Microbiome profile and calprotectin levels as markers of risk of recurrent Clostridioides difficile infection

S Vázquez-Cuesta, N Lozano García… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Clostridioides difficile infection (CDI) is the main cause of nosocomial diarrhoea
in developed countries. Recurrent CDI (R-CDI), which affects 20%-30% of patients and …

Epidemiology of Clostridium difficile infection: results of a hospital-based study in Krakow, Poland

J Czepiel, J Kędzierska, G Biesiada… - Epidemiology & …, 2015 - cambridge.org
Over the past two decades Clostridium difficile infection (CDI) has appeared as a major
public health threat. We performed a retrospective study based on the records of patients …

Современные стратегии диагностики и лечения Clostridium difficile-инфекции (обзор литературы)

ИВ Николаева, ИВ Шестакова… - Acta Biomedica …, 2018 - cyberleninka.ru
Частота и смертность от Clostridium difficile-инфекции (КДИ) за последние 10-20 лет
значительно возросла. КДИ является ведущей причиной антибиотик-ассоциированной …