Oxytocin and vasopressin agonists and antagonists as research tools and potential therapeutics

M Manning, A Misicka, A Olma… - Journal of …, 2012 - Wiley Online Library
We recently reviewed the status of peptide and nonpeptide agonists and antagonists for the
V1a, V1b and V2 receptors for arginine vasopressin (AVP) and the oxytocin receptor for …

Peptide and non-peptide agonists and antagonists for the vasopressin and oxytocin V1a, V1b, V2 and OT receptors: research tools and potential therapeutic agents

M Manning, S Stoev, B Chini, T Durroux… - Progress in brain …, 2008 - Elsevier
Oxytocin (OT) and vasopressin (AVP) mediate their biological actions by acting on four
known receptors: The OT (uterine) and the AVP V 1a (vasopressor), V 1b (pituitary), V 2 …

Comparative distribution of vasopressin V1b and oxytocin receptor messenger ribonucleic acids in brain

C Vaccari, SJ Lolait, NL Ostrowski - Endocrinology, 1998 - academic.oup.com
The comparative distributions of the vasopressin V1b receptor (V1bR) and the oxytocin
receptor (OTR) messenger RNAs (mRNAs) are described in male rat brain using in situ …

Localization and pharmacological characterization of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography

E Tribollet, C Barberis, S Jard, M Dubois-Dauphin… - Brain research, 1988 - Elsevier
Sites which bind tritiated vasopressin (AVP) with high affinity were detected in the brain of
male, adult rats, by light microscopic autoradiography. Their anatomical localization differed …

Molecular cloning and expression of a rat Via arginine vasopressin receptor

A Morel, AM O'Carroll, MJ Brownstein, SJ Lolaft - Nature, 1992 - nature.com
THE neurohypophyseal hormone arginine vasopressin has diverse actions1–7, including
the inhibition of diuresis, contraction of smooth muscle, stimulation of liver glycogenolysis …

Cellular localization of vasopressin V1a receptor messenger ribonucleic acid in adult male rat brain, pineal, and brain vasculature

NL Ostrowski, SJ Lolait, WS Young - Endocrinology, 1994 - academic.oup.com
Vasopressin V1a receptor (V1aR) transcripts were localized in brain, pineal, and superficial
brain vascular tissues of adult male rats using hybridization histochemistry and an [35S] …

Drugs five years later: desmopressin

DW RICHARDSON, AG ROBINSON - Annals of internal medicine, 1985 - acpjournals.org
Desmopressin (dDAVP), a synthetic analog of the neurohypophyseal nonapeptide arginine
vasopressin, has enhanced antidiuretic potency, markedly diminished pressor activity, and a …

125I-labelled d (CH2) 5 [Tyr (Me) 2, Thr4, Tyr-NH29] OVT: a selective oxytocin receptor ligand

J Elands, C Barberis, S Jard, E Tribollet… - European journal of …, 1988 - Elsevier
Abstract An oxytocic antagonist,[1-(β-mercapto-β, β-cyclopentamethylenepropionic acid, 2-O-
methyltyrosine, 4-threonine, 8-ornithine, 9-tyrosylamide] vasotocin (d (CH 2) 5 [Tyr (Me) 2 …

Vasopressin antagonists allow demonstration of a novel type of vasopressin receptor in the rat adenohypophysis.

S Jard, RC Gaillard, G Guillon… - Molecular …, 1986 - molpharm.aspetjournals.org
The ligand specificity of rat adenohypophyseal vasopressin receptors was directly compared
to that of peripheral receptors of the V1 and V2 types. For this purpose a series of 15 recently …

Distribution of messenger RNA for the vasopressin V1a receptor in the CNS of male and female rats

P Szot, TL Bale, DM Dorsa - Molecular brain research, 1994 - Elsevier
The distribution of cells expressing mRNA encoding a vasopressin V 1a receptor (V 1a R)
was examined in Long-Evans male and female rats by in situ hybridization using a [35 S] …