Lactate metabolism in human health and disease

X Li, Y Yang, B Zhang, X Lin, X Fu, Y An… - Signal transduction and …, 2022 - nature.com
The current understanding of lactate extends from its origins as a byproduct of glycolysis to
its role in tumor metabolism, as identified by studies on the Warburg effect. The lactate …

The value of blood lactate kinetics in critically ill patients: a systematic review

JL Vincent, A Quintairos e Silva, L Couto, FS Taccone - Critical care, 2016 - Springer
Background The time course of blood lactate levels could be helpful to assess a patient's
response to therapy. Although the focus of published studies has been largely on septic …

2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery

A Wahba, M Milojevic, C Boer… - European Journal of …, 2020 - academic.oup.com
The invention of CPB revolutionized cardiac surgery. This vital tool has been continuously
refined over the years. Today, achieving excellent results depends on a team approach and …

Severe hyperlactatemia, lactate clearance and mortality in unselected critically ill patients

SA Haas, T Lange, B Saugel, M Petzoldt… - Intensive care …, 2016 - Springer
Purpose Hyperlactatemia may occur for a variety of reasons and is a predictor of poor
clinical outcome. However, only limited data are available on the underlying causes of …

[HTML][HTML] Managing the coagulopathy associated with cardiopulmonary bypass

J Bartoszko, K Karkouti - Journal of Thrombosis and Haemostasis, 2021 - Elsevier
Cardiopulmonary bypass (CPB) has allowed for significant surgical advancements, but
accompanying risks can be significant and must be expertly managed. One of the foremost …

Postoperative critical care of the adult cardiac surgical patient. Part I: routine postoperative care

RS Stephens, GJR Whitman - Critical care medicine, 2015 - journals.lww.com
Objectives: Cardiac surgery, including coronary artery bypass, cardiac valve, and aortic
procedures, is among the most common surgical procedures performed in the United States …

Hyperlactatemia and cardiac surgery

J Minton, DA Sidebotham - The Journal of ExtraCorporeal …, 2017 - ject.edpsciences.org
The normal blood lactate level is 0–2 mmol/L, and a value above 3–5 mmol/L is variably
used to define hyperlactatemia. In cardiac surgical patients, hyperlactatemia can arise from …

Postoperative complications of patients undergoing cardiac surgery

L Ball, F Costantino, P Pelosi - Current opinion in critical care, 2016 - journals.lww.com
Postoperative complications of patients undergoing cardiac s... : Current Opinion in Critical
Care Postoperative complications of patients undergoing cardiac surgery : Current Opinion in …

2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery

G Kunst, M Milojevic, C Boer… - British journal of …, 2019 - bjanaesthesia.org
716-Kunst et al. according to the study design and the internal hierarchy based on the study
quality were used to formulate levels and grades of recommendations. In the absence of …

[HTML][HTML] Venoarterial extracorporeal membrane oxygenation for postcardiotomy shock: risk factors for mortality

T Fux, M Holm, M Corbascio, LH Lund… - The Journal of Thoracic …, 2018 - Elsevier
Objectives Refractory postcardiotomy cardiogenic shock is associated with a high mortality,
and venoarterial extracorporeal membrane oxygenation can offer acute cardiopulmonary life …