Emerging therapeutic options for follicular-derived thyroid cancer in the era of immunotherapy

N Turner, S Hamidi, R Ouni, R Rico… - Frontiers in …, 2024 - frontiersin.org
Although most follicular-derived thyroid cancers are well differentiated and have an overall
excellent prognosis following treatment with surgery and radioiodine, management of …

An update on redifferentiation strategies for radioactive iodine-refractory differentiated thyroid carcinoma

T Pappa, L Wirth - Endocrine, 2024 - Springer
Purpose Although most patients with differentiated thyroid carcinoma (DTC) have an
excellent prognosis, a subset will experience radioactive iodine refractory (RAI-R) disease …

Radioiodine-refractory thyroid cancer—is it time to change the definition in light of novel redifferentiation therapies?

P Petranović Ovčariček, B de Keizer… - European journal of …, 2024 - Springer
The management of differentiated thyroid cancer (DTC) relies on the effectiveness of
radioiodine therapy (RIT), a cornerstone treatment that uses the ability of thyroid cells to …

Multifocal Papillary Thyroid Carcinomas With Discordant Molecular Drivers: Emphasizing the Morphology and Collision Tumors

JP Rivera, YC Yeh, PCH Chen… - The American Journal of …, 2024 - journals.lww.com
Multifocal papillary thyroid carcinomas (PTCs) are common and the majority of the tumors
harbor mutual BRAF p. V600E mutation. This study aimed to investigate a contemporary …

Current status of the prediction for radio-iodine refractory thyroid cancer: a narrative review

Y Wang, X Lu, H Liu - Frontiers in Endocrinology, 2024 - frontiersin.org
It is well established that patients with the most differentiated thyroid cancers have a good
prognosis, whereas when the disease develops into radio-iodine refractory thyroid cancer …

[HTML][HTML] Redifferentiation Therapies in Thyroid Oncology: Molecular and Clinical Aspects

P Petranović Ovčariček, M Tuncel, A Aghaee… - Journal of clinical …, 2024 - mdpi.com
Since the 1940s, 131-I radioiodine therapy (RIT) has been the primary treatment for
metastatic differentiated thyroid cancer (DTC). Approximately half of these patients respond …

125I seed implantation for lymph node metastasis from radioactive iodine-refractory differentiated thyroid carcinoma: a study on short-term efficacy and dosimetry

W Zhang, S Hao, Z Wang, T Ding… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
Objective To investigate the feasibility and evaluate the safety and effectiveness of
Computed Tomography (CT) guided125I radioactive particle implantation for treating lymph …

Redifferentiation Therapy in Iodine Refractory Differentiated Thyroid Cancer: The Verdict Is Still Out

L Castellanos, TD Cubb - Clinical Thyroidology®, 2024 - liebertpub.com
Background Although differentiated thyroid cancer (DTC) is generally indolent, DTC with
progressive, persistent, or recurrent distant metastatic disease has a poor prognosis. 1 …

国内におけるRAI 内用療法の現状と将来展望

廣正智, 絹谷清剛 - 日本内分泌外科学会雑誌, 2024 - jstage.jst.go.jp
抄録 今回の甲状腺腫瘍診療ガイドライン改定において, 甲状腺分化癌に対する放射性ヨウ素 (RAI:
radioactive iodine) 内用療法では特に補助療法に焦点が当てられた. 国内外における RAI …

[引用][C] Redifferentiation of a RET-Fusion, Radioiodine-Refractory, Differentiated Thyroid Cancer with Selpercatinib: Flip-Flop Between [18F] FDG PET/CT and 131I …

F Barbry, B Chevalier, A Beron, G Lion… - Journal of Nuclear …, 2025 - jnm.snmjournals.org
A29-y-old woman requiring total thyroidectomy with lymph node dissection for a stage pT3
(m) N1bMxR2 solid variant of papillary thyroid cancer had, near the left recurrent vagal …