Research progress in brain-targeted nasal drug delivery

Q Huang, X Chen, S Yu, G Gong, H Shu - Frontiers in Aging …, 2024 - frontiersin.org
The unique anatomical and physiological connections between the nasal cavity and brain
provide a pathway for bypassing the blood–brain barrier to allow for direct brain-targeted …

Arsenic unsettles the cerebellar balance between neurodegeneration and neurogenesis: reversal by folic acid

A Das, A Mitra, S Sarkar, S Ghosh, D Bandyopadhyay… - Apoptosis, 2024 - Springer
Arsenic-mediated neurodegenerative disorders affect millions of individuals globally, but the
specific impact of environmental arsenic on adult cerebellar degeneration and neurogenesis …

[HTML][HTML] Metabolomics Reveal Key Metabolic Pathway Responses to Anxiety State Regulated by Serotonin in Portunus trituberculatus

W Zhai, Y Fu, L Liu, X Huang, S Wang - Metabolites, 2024 - mdpi.com
Background: Anxiety refers to the pathological persistence and intensification of emotional
responses to danger, affecting health from psychological and physical aspects. Serotonin is …

Zinc Gluconate Supplementation Protects against Methotrexate-induced Neurotoxicity in Rats via Downregulation of Oxidative Stress, Inflammation and Neuron …

AT Olofinnade, AY Onaolapo, OB Okunola… - Current …, 2024 - benthamdirect.com
Background The global increase in the incidence of cancers, as well as neurotoxicity
induced by cancer therapy, has necessitated research into agents that are neuroprotective …

Dietary zinc protects against methotrexate-induced neurotoxicity in rats via modulation of oxidative stress, inflammation and neuronal energy metabolism

AY Onaolapo, OB Okunola, AT Olofinnade… - bioRxiv, 2023 - biorxiv.org
Background Increasing incidence of cancers and cancer chemotherapy-induced
neurotoxicities makes it imperative to research compounds with neuroprotective potential …