Prevotella diversity, niches and interactions with the human host

A Tett, E Pasolli, G Masetti, D Ercolini… - Nature Reviews …, 2021 - nature.com
The genus Prevotella includes more than 50 characterized species that occur in varied
natural habitats, although most Prevotella spp. are associated with humans. In the human …

Gut microbiota in human metabolic health and disease

Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …

Environmental factors shaping the gut microbiome in a Dutch population

R Gacesa, A Kurilshikov, A Vich Vila, T Sinha… - Nature, 2022 - nature.com
The gut microbiome is associated with diverse diseases–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

[HTML][HTML] Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

KA Lee, AM Thomas, LA Bolte, JR Björk… - Nature Medicine, 2022 - nature.com
The composition of the gut microbiome has been associated with clinical responses to
immune checkpoint inhibitor (ICI) treatment, but there is limited consensus on the specific …

[HTML][HTML] Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4

A Blanco-Míguez, F Beghini, F Cumbo, LJ McIver… - Nature …, 2023 - nature.com
Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

Autism-related dietary preferences mediate autism-gut microbiome associations

CX Yap, AK Henders, GA Alvares, DLA Wood… - Cell, 2021 - cell.com
There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have …

[HTML][HTML] Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19

YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li… - Gut, 2021 - gut.bmj.com
Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence
suggesting that the GI tract is involved in this disease. We investigated whether the gut …

[HTML][HTML] Reconstruction of ancient microbial genomes from the human gut

MC Wibowo, Z Yang, M Borry, A Hübner, KD Huang… - Nature, 2021 - nature.com
Loss of gut microbial diversity–in industrial populations is associated with chronic diseases,
underscoring the importance of studying our ancestral gut microbiome. However, relatively …

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

DD Wang, LH Nguyen, Y Li, Y Yan, W Ma, E Rinott… - Nature medicine, 2021 - nature.com
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …

inStrain profiles population microdiversity from metagenomic data and sensitively detects shared microbial strains

MR Olm, A Crits-Christoph, K Bouma-Gregson… - Nature …, 2021 - nature.com
Coexisting microbial cells of the same species often exhibit genetic variation that can affect
phenotypes ranging from nutrient preference to pathogenicity. Here we present inStrain, a …