As a multitargeted kinase inhibitor, sunitinib has carved its way into demonstrating itself as a
most effective tyrosine kinase inhibitor in the treatment of metastatic renal cell carcinoma …

Human cytomegalovirus (HCMV) infection is associated with severe morbidity and mortality
in immunocompromised individuals, in particular transplant recipients and AIDS patients …

DNA glycosylases are enzymes that initiate the base excision repair pathway, a major
biochemical process that protects the genomes of all living organisms from intrinsically and …

Human herpesviruses are found worldwide and are among the most frequent causes of viral
infections in immunocompetent as well as in immunocompromised patients. During the past …

The quiet pandemic of herpes simplex virus (HSV) infections has plagued humanity since
ancient times, causing mucocutaneous infection such as herpes labialis and herpes …

Recently, we have reported a series of new 1, 3-symmetrically (R1= R3) substituted
xanthines (3 and 4) which have high affinity and selectivity for the human adenosine A2B …

The quiet pandemic of herpes simplex virus (HSV) infection has plagued humanity since
ancient times, causing mucocutaneous infection, such as herpes labialis and herpes …

Uracil–DNA glycosylases are enzymes that excise uracil bases appearing in DNA as a
result of cytosine deamination or accidental dUMP incorporation from the dUTP pool. The …

A library of fused pyridine-4-carboxylic acids (including pyrazolo [3, 4-b] pyridines, isoxazolo
[5, 4-b] pyridines, furo [2, 3-b] pyridines, thieno [2, 3-b] pyridines, and pyrido [2, 3-d] …

N-Heterocyclic carbenes (NHCs) catalyzing aza-Claisen rearrangement of α, β-unsaturated
enals with cyclic vinylogous amides under oxidative conditions generating potentially …