The three endogenous gaseous transmitters—nitric oxide (NO), carbon monoxide (CO) and
hydrogen sulfide (H2S)—regulate a number of key biological functions. Emerging data have …

Heme oxygenase-1 (HO-1) is an inducible intracellular enzyme that is expressed in
response to a variety of stimuli to degrade heme, which generates the biologically active …

Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

Carbon monoxide-releasing molecules (CORMs) are chemical agents used to administer
CO as an endogenous, biologically active molecule. A precise spatial and temporal control …

Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …

The upregulation of heme oxygenase-1 (HO-1) is one of the most important mechanisms of
cell adaptation to stress. Indeed, the redox sensitive transcription factor Nrf2 is the pivotal …

Metal-organic frameworks (MOFs) are a novel class of porous materials made from metal
ions and organic ligands, and have been widely explored as multifunctional nanoplatforms …

NIR-responsive on-demand release of CO from metal carbonyl-caged graphene oxide
nanomedicine - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Abstract Heme oxygenase-1 (HO-1, hmox-1) catalyzes the rate-limiting step in the heme
degradation processes. Out of three by-products of HO-1 activity, biliverdin, iron ions and …

Carbon monoxide (CO) therapy has emerged as a hot topic under exploration in the field of
gas therapy as it shows the promise of treating various diseases. Due to the gaseous …