Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …

Several challenges to current views of thalamocortical processing are offered here.
Glutamatergic pathways in thalamus and cortex are divided into two distinct classes: driver …

Humans and many other animals have an enormous capacity to learn about sensory stimuli
and to master new skills. However, many of the mechanisms that enable us to learn remain …

Neocortex, the neuronal structure at the base of the remarkable cognitive skills of mammals,
is a layered sheet of neuronal tissue composed of juxtaposed and interconnected columns …

Tactile information is actively acquired and processed in the brain through concerted
interactions between movement and sensation. Somatosensory input is often the result of …

The previous editions of The Rat Nervous System were indispensable guides for those
working on the rat and mouse as experimental models. The fourth edition enhances this …

Neocortical areas are believed to be organized into vertical modules, the cortical columns,
and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined …

The primary somatosensory barrel cortex processes tactile vibrissae information, allowing
rodents to actively perceive spatial and textural features of their immediate surroundings …

This review attempts to summarise some of the major areas of neocortical research as it
pertains to layer 6. After a brief summary of the development of this intriguing layer, the …

Layer V pyramidal neurons are anatomically and physiologically heterogeneous and project
to multiple intracortical and subcortical targets. However, because most physiological …