The dynamics, distribution and activity of subcellular organelles are integral to regulating
cell shape changes during various physiological processes such as epithelial cell formation …

During morphogenesis, changes in the shapes of individual cells are harnessed to mold an
entire tissue. These changes in cell shapes require the coupled remodeling of the plasma …

Animals must adapt their growth to fluctuations in nutrient availability to ensure proper
development. These adaptations often rely on specific nutrient-sensing tissues that control …

Optimal mitochondrial function determined by mitochondrial dynamics, morphology and
activity is coupled to stem cell differentiation and organism development. However, the …

The workhorse of developmental biology is the confocal microscope, which allows
researchers to determine the three-dimensional localization of tagged molecules within …

Embryos undergo pre-gastrulation cleavage cycles to generate a critical cell mass before
transitioning to morphogenesis. The molecular underpinnings of this transition have …

Mitochondria are relatively small, fragmented, and abundant in the large embryos of
Drosophila, Xenopus and zebrafish. It is essential to study their distribution and dynamics in …

Mitochondrial morphology dynamics regulate signaling pathways during epithelial cell
formation and differentiation. The mitochondrial fission protein Drp1 affects the appropriate …

Mitochondria are highly dynamic organelles that undergo morphological changes through a
system of fission and fusion. Throughout interphase mitochondria primarily exist as large …

Mitochondria are not static organelles, but instead are dynamic networks that undergo rapid
changes in subcellular distribution, organization, and activity in response to external stimuli …