Current (high throughput omics-based) data support the model that human (malignant) germ
cell tumors are not initiated by somatic mutations, but, instead through a defined locked …

Globally, testicular cancer incidence is highest among men of northern European ancestry
and lowest among men of Asian and African descent. Incidence rates have been increasing …

Background Incidence rates of testicular cancer (TC) have been increasing in many
countries since, at least, the mid-20th century without clear explanation. Examining the …

Incidence rates of testicular cancer in Northern European and North American countries
have been widely reported, whereas rates in other populations, such as Eastern Europe …

Background: Whereas testicular cancer incidence rates have been widely reported in
populations of Northern European ancestry, rates in other populations have been less …

Purpose Increasing in incidence, testicular cancer is the most commonly diagnosed cancer
in young men in the USA and in Europe. We sought to determine contemporary trends in …

Testicular germ cell tumors (TGCT), which comprise 98% of all testicular malignancies, are
the most commonly occurring cancers among men between the ages of 15 and 44 years in …

BACKGROUND: Pediatric germ cell tumors (GCTs) are rare and heterogeneous tumors with
uncertain etiology. In the current study, data from the National Cancer Institute's …

Progressive increases in the incidence of male reproductive disorders inclusive of
hypospadias, cryptorchidism, poor semen quality, and testicular germ cell cancer (TGCC) …

Background Covalent RNA modifications, such as N-6-methyladenosine (m 6 A), have been
associated with various biological processes, but their role in cancer remains largely …