Theory of the multiregional neocortex: large-scale neural dynamics and distributed cognition

XJ Wang - Annual review of neuroscience, 2022 - annualreviews.org
The neocortex is a complex neurobiological system with many interacting regions. How
these regions work together to subserve flexible behavior and cognition has become …

Timescales of learning in prefrontal cortex

JA Miller, C Constantinidis - Nature Reviews Neuroscience, 2024 - nature.com
The lateral prefrontal cortex (PFC) in humans and other primates is critical for immediate,
goal-directed behaviour and working memory, which are classically considered distinct from …

Long-term learning transforms prefrontal cortex representations during working memory

JA Miller, A Tambini, A Kiyonaga, M D'Esposito - Neuron, 2022 - cell.com
The role of the lateral prefrontal cortex (lPFC) in working memory (WM) is debated. Non-
human primate (NHP) electrophysiology shows that the lPFC stores WM representations, but …

Curiosity: primate neural circuits for novelty and information seeking

IE Monosov - Nature Reviews Neuroscience, 2024 - nature.com
For many years, neuroscientists have investigated the behavioural, computational and
neurobiological mechanisms that support value-based decisions, revealing how humans …

The neural basis of resting-state fMRI functional connectivity in fronto-limbic circuits revealed by chemogenetic manipulation

C Elorette, A Fujimoto, FM Stoll, SH Fujimoto… - Nature …, 2024 - nature.com
Measures of fMRI resting-state functional connectivity (rs-FC) are an essential tool for basic
and clinical investigations of fronto-limbic circuits. Understanding the relationship between …

Intrinsic neural timescales in the temporal lobe support an auditory processing hierarchy

R Cusinato, SL Alnes, E van Maren… - Journal of …, 2023 - Soc Neuroscience
During rest, intrinsic neural dynamics manifest at multiple timescales, which progressively
increase along visual and somatosensory hierarchies. Theoretically, intrinsic timescales are …

Atypical intrinsic neural timescales in temporal lobe epilepsy

K Xie, J Royer, S Lariviere, R Rodriguez‐Cruces… - …, 2023 - Wiley Online Library
Objective Temporal lobe epilepsy (TLE) is the most common pharmacoresistant epilepsy in
adults. Here we profiled local neural function in TLE in vivo, building on prior evidence that …

Deciphering the functional specialization of whole-brain spatiomolecular gradients in the adult brain

JW Vogel, AF Alexander-Bloch… - Proceedings of the …, 2024 - National Acad Sciences
Cortical arealization arises during neurodevelopment from the confluence of molecular
gradients representing patterned expression of morphogens and transcription factors …

Cortical timescales and the modular organization of structural and functional brain networks

DJ Lurie, I Pappas, M D'Esposito - Human Brain Mapping, 2024 - Wiley Online Library
Recent years have seen growing interest in characterizing the properties of regional brain
dynamics and their relationship to other features of brain structure and function. In particular …

Hierarchical gradients of multiple timescales in the mammalian forebrain

M Song, EJ Shin, H Seo, A Soltani… - Proceedings of the …, 2024 - pnas.org
Many anatomical and physiological features of cortical circuits, ranging from the biophysical
properties of synapses to the connectivity patterns among different neuron types, exhibit …