The emergence and influence of internal states
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …
profoundly shape perception, cognition, and action. The neural basis of internal states, such …
Social isolation and the brain: effects and mechanisms
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …
reduction in social interaction, which is associated with many adverse effects on health in …
[HTML][HTML] The neuropeptide Tac2 controls a distributed brain state induced by chronic social isolation stress
Chronic social isolation causes severe psychological effects in humans, but their neural
bases remain poorly understood. 2 weeks (but not 24 hr) of social isolation stress (SIS) …
bases remain poorly understood. 2 weeks (but not 24 hr) of social isolation stress (SIS) …
Multimodal mapping of cell types and projections in the central nucleus of the amygdala
The central nucleus of the amygdala (CEA) is a brain region that integrates external and
internal sensory information and executes innate and adaptive behaviors through distinct …
internal sensory information and executes innate and adaptive behaviors through distinct …
Sex differences in neural projections of fear memory processing in mice and humans
A Florido, ER Velasco, LR Romero, N Acharya… - Science …, 2024 - science.org
It remains unexplored in the field of fear memory whether functional neuronal connectivity
between two brain areas is necessary for one sex but not the other. Here, we show that …
between two brain areas is necessary for one sex but not the other. Here, we show that …
Amygdala-midbrain connections modulate appetitive and aversive learning
EE Steinberg, F Gore, BD Heifets, MD Taylor… - Neuron, 2020 - cell.com
The central amygdala (CeA) orchestrates adaptive responses to emotional events. While
CeA substrates for defensive behaviors have been studied extensively, CeA circuits for …
CeA substrates for defensive behaviors have been studied extensively, CeA circuits for …
Quantified coexpression analysis of central amygdala subpopulations
Molecular identification and characterization of fear controlling circuitries is a promising path
towards developing targeted treatments of fear-related disorders. Three-color in situ …
towards developing targeted treatments of fear-related disorders. Three-color in situ …
Central amygdala circuits in valence and salience processing
MS Kong, LS Zweifel - Behavioural brain research, 2021 - Elsevier
Behavioral responses to environmental stimuli are dictated by the affective valence of the
stimulus, good (positive valence) or bad (negative valence). These stimuli can innately elicit …
stimulus, good (positive valence) or bad (negative valence). These stimuli can innately elicit …
Microglial homeostasis requires balanced CSF-1/CSF-2 receptor signaling
CSF-1R haploinsufficiency causes adult-onset leukoencephalopathy with axonal spheroids
and pigmented glia (ALSP). Previous studies in the Csf1r+/− mouse model of ALSP …
and pigmented glia (ALSP). Previous studies in the Csf1r+/− mouse model of ALSP …
Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear
The lateral central nucleus of the amygdala (CeA L) and the dorsolateral bed nucleus of the
stria terminalis (BNST DL) coordinate the expression of shorter-and longer-lasting fears …
stria terminalis (BNST DL) coordinate the expression of shorter-and longer-lasting fears …