Well-orchestrated maternal–fetal cross talk occurs via secreted ligands, interacting
receptors, and coupled intracellular pathways between the conceptus and endometrium and …

Increasing evidence suggests different, not completely understood roles of microRNA
biogenesis in the development and progression of lung cancer. The overexpression of the …

Methods We used The Cancer Genome Atlas (commonly known as TCGA) data analysis to
evaluate the expression of APE1 in HCC. To identify differentially-expressed miRNAs …

Although pathways are widely used for the analysis and representation of biological
systems, their lack of clear boundaries, their dispersion across numerous databases, and …

Background Pancreatic cancer (PC) is a complex disease in which both non-genetic and
genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in …

Huntington's disease is a rare neurodegenerative disease caused by a cytosine–adenine–
guanine (CAG) trinucleotide expansion in the Huntingtin (HTT) gene. Although Huntington's …

Background The complexity of representing biological systems is compounded by an ever-
expanding body of knowledge emerging from multi-omics experiments. A number of …

In worldwide, lung cancer has a major socio-economic impact and is one of the most
common causes of cancer-related deaths. Current therapies for lung cancer are still quite …

PathIN is a web-service that provides an easy and flexible way for rapidly creating pathway-
based networks at several functional biological levels: genes, compounds and reactions …

Extracellular matrix (ECM)-related adhesion proteins are important in metastasis. Ras
suppressor-1 (RSU-1), a suppressor of Ras-transformation, is localized to cell–ECM …