Pathogenesis and virulence of Candida albicans

JP Lopes, MS Lionakis - Virulence, 2022 - Taylor & Francis
Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Immune defence to invasive fungal infections: A comprehensive review

B Pathakumari, G Liang, W Liu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

The mycobiota: interactions between commensal fungi and the host immune system

DM Underhill, ID Iliev - Nature Reviews Immunology, 2014 - nature.com
The body is host to a wide variety of microbial communities from which the immune system
protects us and that are important for the normal development of the immune system and for …

Fungal dysbiosis: immunity and interactions at mucosal barriers

ID Iliev, I Leonardi - Nature Reviews Immunology, 2017 - nature.com
Fungi and mammals share a co-evolutionary history and are involved in a complex web of
interactions. Studies focused on commensal bacteria suggest that pathological changes in …

[HTML][HTML] Kynurenine emerges from the shadows–Current knowledge on its fate and function

M Marszalek-Grabska, K Walczak, K Gawel… - Pharmacology & …, 2021 - Elsevier
Kynurenine (KYN), a main metabolite of tryptophan in mammals, is a direct precursor of
kynurenic acid, anthranilic acid and 3-hydroxykynurenine (3-HK). Under physiological …

Gut mycobiota in immunity and inflammatory disease

XV Li, I Leonardi, ID Iliev - Immunity, 2019 - cell.com
The mammalian intestine is colonized by a wealth of microorganisms—including bacteria,
viruses, protozoa, and fungi—that are all integrated into a functional trans-kingdom …

Vulvovaginal Candida albicans infections: pathogenesis, immunity and vaccine prospects

A Cassone - BJOG: An International Journal of Obstetrics & …, 2015 - Wiley Online Library
Although a number of fungal species belonging to the genus C andida can cause acute
vulvovaginal infection (VVC), C andida albicans is by far the most prevalent etiological …

Recurrent vulvovaginal candidiasis

JD Sobel - American journal of obstetrics and gynecology, 2016 - Elsevier
Recurrent vulvovaginal candidiasis (RVVC) is a common cause of significant morbidity in
women in all strata of society affecting millions of women worldwide. Previously, RVVC …