Inner hair cell loss disrupts hearing and cochlear function leading to sensory deprivation and enhanced central auditory gain

R Salvi, W Sun, D Ding, GD Chen… - Frontiers in …, 2017 - frontiersin.org
There are three times as many outer hair cells (OHC) as inner hair cells (IHC), yet IHC
transmit virtually all acoustic information to the brain as they synapse with 90–95% of type I …

Hearing loss: Determining eligibility for social security benefits

SB Van Hemel, RA Dobie - 2004 - books.google.com
Millions of Americans experience some degree of hearing loss. The Social Security
Administration (SSA) operates programs that provide cash disability benefits to people with …

Characteristics of DPOAE audiogram in tinnitus patients

Y Shiomi, J Tsuji, Y Naito, N Fujiki, N Yamamoto - Hearing research, 1997 - Elsevier
To investigate cochlear activity in tinnitus, the DPOAE (distortion product otoacoustic
emission) audiograms (DP-gram) of tinnitus patients were measured. Nine tinnitus patients …

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

P Chen, F Zindy, C Abdala, F Liu, X Li, MF Roussel… - Nature cell …, 2003 - nature.com
Maintenance of the post-mitotic state in the post-natal mammalian brain is an active process
that requires the cyclin-dependent kinase inhibitors (CKIs) p19Ink4d (Ink4d) and p27Kip1 …

Selective inner hair cell loss does not alter distortion product otoacoustic emissions

P Trautwein, P Hofstetter, J Wang, R Salvi, A Nostrant - Hearing research, 1996 - Elsevier
Outer hair cells (OHC) are believed to be the dominant source of distortion product
otoacoustic emissions (DPOAE) in mammals; however, some studies in genetic mutants …

Quantitative relationship of carboplatin dose to magnitude of inner and outer hair cell loss and the reduction in distortion product otoacoustic emission amplitude in …

P Hofstetter, D Ding, N Powers, RJ Salvi - Hearing research, 1997 - Elsevier
The outer hair cells (OHCs) are thought to be the dominant source of distortion product
otoacoustic emissions (DPOAEs) in the mammalian cochlea; however, little is known about …

Sensitivity of distortion-product otoacoustic emissions in humans to tonal over-exposure: time course of recovery and effects of lowering L2

LA Sutton, BL Lonsbury-Martin, GK Martin… - Hearing research, 1994 - Elsevier
An important concern of industrial hearing-conservation programs is detecting the onset of
noise-induced hearing loss. If it can he shown that otoacoustic emissions are sufficiently …

Auditory efferent feedback system deficits precede age‐related hearing loss: Contralateral suppression of otoacoustic emissions in mice

X Zhu, ON Vasilyeva, S Kim… - Journal of …, 2007 - Wiley Online Library
Abstract The C57BL/6J mouse has been a useful model of presbycusis, as it displays an
accelerated age‐related peripheral hearing loss. The medial olivocochlear efferent …

Variation of distortion product otoacoustic emissions with furosemide injection

DM Mills, EW Rubel - Hearing research, 1994 - Elsevier
Cochlear function was monitored in adult gerbils using distortion product otoacoustic
emissions (DPOAE) during intraperitoneal injection of furosemide. All stimulus parameters …

Distortion product otoacoustic emissions and sensorineural hearing loss

A Moulin, JC Bera, L Collet - Audiology, 1994 - Taylor & Francis
As other types of otoacoustic emissions, distortion product otoacoustic emissions (DPOAEs)
allow the exploration of the active cochlear mechanisms known to take place in the outer …