The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research
NF Walker, C Stek, S Wasserman… - Current Opinion in …, 2018 - journals.lww.com
Specific biomarkers would aid in identifying high-risk patients for interventions and a
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …
diagnostic test is needed. Clinicians should consider prednisone for TB-IRIS prevention in …
Inflammation: the driver of poor outcomes among children with severe acute malnutrition?
Severe acute malnutrition (SAM) is the most life-threatening form of undernutrition and
underlies at least 10% of all deaths among children younger than 5 years in low-income …
underlies at least 10% of all deaths among children younger than 5 years in low-income …
CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study
Background Tuberculosis remains a leading cause of global mortality, especially for adults
and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum …
and children living with HIV (CLHIV) underdiagnosed by sputum-based assays. Non-sputum …
Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
Sensitive and specific blood-based assays for the detection of pulmonary and
extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses …
extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses …
Adapting HIV services for pregnant and breastfeeding women, infants, children, adolescents and families in resource‐constrained settings during the COVID‐19 …
AC Vrazo, R Golin, NB Fernando… - Journal of the …, 2020 - Wiley Online Library
Introduction The COVID‐19 pandemic has impacted global health service delivery, including
provision of HIV services. Countries with high HIV burden are balancing the need to …
provision of HIV services. Countries with high HIV burden are balancing the need to …
[HTML][HTML] Risk factors for postdischarge mortality following hospitalization for severe acute malnutrition in Zimbabwe and Zambia
M Bwakura-Dangarembizi, C Dumbura, B Amadi… - The American journal of …, 2021 - Elsevier
Background Children discharged from hospital following management of complicated
severe acute malnutrition (SAM) have a high risk of mortality, especially HIV-positive …
severe acute malnutrition (SAM) have a high risk of mortality, especially HIV-positive …
Monocyte-to-lymphocyte ratio is associated with tuberculosis disease and declines with anti-TB treatment in HIV-infected children
Background: The blood monocyte-to-lymphocyte ratio (MLR) is associated with active
tuberculosis (TB) in adults but has not been evaluated as a TB diagnostic biomarker in HIV …
tuberculosis (TB) in adults but has not been evaluated as a TB diagnostic biomarker in HIV …
[HTML][HTML] A global research agenda for pediatric HIV
M Penazzato, C Irvine, M Vicari… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Despite progress, 2016 still saw 160,000 new infections and 120,000 AIDS-
related deaths among children. Evidence gaps on how to best diagnose, treat, and deliver …
related deaths among children. Evidence gaps on how to best diagnose, treat, and deliver …
[HTML][HTML] Postdischarge interventions for children hospitalized with severe acute malnutrition: a systematic review and meta-analysis
CCA Noble, JP Sturgeon… - The American journal of …, 2021 - Elsevier
Background Children hospitalized with severe acute malnutrition (SAM) have poor long-term
outcomes following discharge, with high rates of mortality, morbidity, and impaired …
outcomes following discharge, with high rates of mortality, morbidity, and impaired …
[HTML][HTML] Assay design for unambiguous identification and quantification of circulating pathogen-derived peptide biomarkers
Rationale: Circulating pathogen-derived proteins can serve as useful biomarkers for
infections but may be detected with poor sensitivity and specificity by standard …
infections but may be detected with poor sensitivity and specificity by standard …