The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

The solid‐form screening of active principal ingredients is a challenge for pharmaceutical
drug development, as more than 80% of marketed drugs are formulated in the solid form. A …

Originally discovered almost a century ago, cocrystals continue to gain interest in the
modern day due to their ability to modify the physical properties of solid-state materials …

The acid··· amide dimer heterosynthon in cocrystals of aromatic acids and primary amides is
identified by marker peaks in the IR spectra that are characteristic of individual N–H··· O and …

Current study is focused to enhance the solubility of poorly soluble drug olanzapine (OLZ)
by nanogels drug delivery system, as improved solubility is one of the most important …

Pharmaceutical cocrystals represent a distinctive class of crystal engineered
multicomponent systems consisting an API and a crystal former non-covalently linked …

In recent years, nanotechnology has offered attractive opportunities to overcome the (bio)
pharmaceutical drawbacks of most drugs such as low aqueous solubility and bioavailability …

Two novel drug–drug (1: 1) cocrystals of berberine chloride (BER) with myricetin (MYR) and
dihydromyricetin (DMY), BER-MYR (1), and BER-DMY (2) have been prepared and …

The cocrystal formation of the anticonvulsant drug carbamazepine (CBZ) with para-
aminosalicylic acid (PASA, antituberculous drug) has been studied by varying the molar …

This work reports two novel drug–drug cocrystals of antifungal clotrimazole (CLT) with
nonsteroidal anti-inflammatory drugs, including niflumic acid (NFA) and diclofenac (DIC) …