Oncolytic viruses (OVs) represent a new class of multi-modal immunotherapies for cancer,
with OV-elicited antitumor immunity being key to their overall therapeutic efficacy. Currently …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

Neuroblastoma (NB) is the most common pediatric tumor malignancy that originates from the
neural crest and accounts for more than 15% of all the childhood deaths from cancer. The …

Myeloid-derived suppressor cells (MDSCs) are immune cells of the myeloid lineage that
progressively accumulate in tumors and play an important role in promoting tumor growth …

Neuroblastoma is the most common extracranial pediatric tumor and often presents with
metastatic disease, and patients with high-risk neuroblastoma have survival rates of~ 50 …

Pancreatic ductal adenocarcinoma (PDAC) usually presents infrequent infiltration of T
lymphocytes. The known immune-checkpoint inhibitors to date focus on activating T cells …

ABSTRACT Introduction Autoimmune diseases (ADs) are disorders induced by multiple
inflammatory mediators, in which immune system attacks healthy tissues and triggers tissue …

The plant kingdom is a source of important therapeutic agents. Therefore, in this review, we
focus on natural compounds that exhibit efficient anti-inflammatory activity via modulation …

Assay for transposase-accessible chromatin using sequencing (ATAC-seq) is associated
with significant progress in biological research and has attracted increasing attention …

Background Neuroblastoma (NB) is considered an immunologically cold tumor and is
usually less responsive to immune checkpoint blockade (ICB). Tumor-associated …