Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease

D Bairamian, S Sha, N Rolhion, H Sokol… - Molecular …, 2022 - Springer
Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Tryptophan metabolism and gut-brain homeostasis

W Roth, K Zadeh, R Vekariya, Y Ge… - International journal of …, 2021 - mdpi.com
Tryptophan is an essential amino acid critical for protein synthesis in humans that has
emerged as a key player in the microbiota-gut-brain axis. It is the only precursor for the …

Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
The human gastrointestinal (gut) microbiota comprises diverse and dynamic populations of
bacteria, archaea, viruses, fungi, and protozoa, coexisting in a mutualistic relationship with …

The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology

T Doifode, VV Giridharan, JS Generoso, G Bhatti… - Pharmacological …, 2021 - Elsevier
The gut microbiota is a complex ecosystem that comprises of more than 100 trillion symbiotic
microbial cells. The microbiota, the gut, and the brain form an association,'the microbiota-gut …

[HTML][HTML] The microbiota-gut-brain axis in hippocampus-dependent learning and memory: current state and future challenges

EJ Kuijer, L Steenbergen - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
A fundamental shift in neuroscience suggests bidirectional interaction of gut microbiota with
the healthy and dysfunctional brain. This microbiota-gut-brain axis has mainly been …

How microbes affect depression: underlying mechanisms via the Gut–brain axis and the modulating role of probiotics

K Suda, K Matsuda - International journal of molecular sciences, 2022 - mdpi.com
Accumulating evidence suggests that the gut microbiome influences the brain functions and
psychological state of its host via the gut–brain axis, and gut dysbiosis has been linked to …

[HTML][HTML] Diet, inflammation and the gut microbiome: mechanisms for obesity-associated cognitive impairment

SJ Leigh, MJ Morris - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Poor diet and obesity are associated with cognitive impairment throughout adulthood, and
increased dementia risk in aging. Here we review the current literature interrogating the …

Probiotic treatment improves the impaired spatial cognitive performance and restores synaptic plasticity in an animal model of Alzheimer's disease

ZR Asl, G Sepehri, M Salami - Behavioural brain research, 2019 - Elsevier
Studies demonstrate that damage to gut microbiota is associated with some brain disorders
including neurodegenerative diseases such as Alzheimer's disease (AD). Accordingly …

Potential roles of gut microbiota and microbial metabolites in Parkinson's disease

SY Zheng, HX Li, RC Xu, WT Miao, MY Dai… - Ageing Research …, 2021 - Elsevier
Parkinson's disease (PD) is a complicated neurodegenerative disease attributed to
multifactorial changes. However, its pathological mechanism remains undetermined …