Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …

Abstract Purpose of Review Mitochondria play various roles that are important for cell
function and survival; therefore, significant mitochondrial dysfunction may have chronic …

Age-related macular degeneration (AMD) is a complex eye disease that affects millions of
people worldwide and is the main reason for legal blindness and vision loss in the elderly in …

The modern concept of DNA-based barcoding for cataloguing biodiversity was proposed in
2003 by first adopting an approximately 600 bp fragment of the mitochondrial COI gene to …

Inflammation is a key process in metazoan organisms due to its relevance for innate defense
against infections and tissue damage. However, inflammation is also implicated in …

Cardiovascular diseases (CVDs) are one of the primary causes of mortality worldwide. An
optimal mitochondrial function is central to supplying tissues with high energy demand, such …

Cancer is a serious health problem with a high mortality rate worldwide. Given the relevance
of mitochondria in numerous physiological and pathological mechanisms, such as …

Background: Atherosclerosis is a chronic inflammatory condition that affects different arteries
in the human body and often leads to severe neurological complications, such as stroke and …

Pancreatic β‑cells are the only source of insulin in humans. Mitochondria uses pyruvate to
produce ATP as an intermediate link between glucose intake and insulin secretion in β‑cells …

Studies have suggested a potential role of somatic mitochondrial mutations in cancer
development. To analyze the landscape of somatic mitochondrial mutation in breast cancer …