The physiological control of eating: signals, neurons, and networks
AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …
Acts of appetite: neural circuits governing the appetitive, consummatory, and terminating phases of feeding
The overconsumption of highly caloric and palatable foods has caused a surge in obesity
rates in the past half century, thereby posing a healthcare challenge due to the array of …
rates in the past half century, thereby posing a healthcare challenge due to the array of …
Genome-wide analysis of a model-derived binge eating disorder phenotype identifies risk loci and implicates iron metabolism
Binge eating disorder (BED) is the most common eating disorder, yet its genetic architecture
remains largely unknown. Studying BED is challenging because it is often comorbid with …
remains largely unknown. Studying BED is challenging because it is often comorbid with …
[HTML][HTML] An orexigenic subnetwork within the human hippocampus
Only recently have more specific circuit-probing techniques become available to inform
previous reports implicating the rodent hippocampus in orexigenic appetitive processing …
previous reports implicating the rodent hippocampus in orexigenic appetitive processing …
[HTML][HTML] Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats
KS Subramanian, LT Lauer, AMR Hayes… - Nature …, 2023 - nature.com
The lateral hypothalamic area (LHA) integrates homeostatic processes and reward-
motivated behaviors. Here we show that LHA neurons that produce melanin-concentrating …
motivated behaviors. Here we show that LHA neurons that produce melanin-concentrating …
Memory and eating: A bidirectional relationship implicated in obesity
This paper reviews evidence demonstrating a bidirectional relationship between memory
and eating in humans and rodents. In humans, amnesia is associated with impaired …
and eating in humans and rodents. In humans, amnesia is associated with impaired …
[HTML][HTML] Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young …
Background The hypothalamus plays a crucial role in regulating sleep-wake cycle and
motivated behavior. Sleep disturbance is associated with impairment in cognitive and …
motivated behavior. Sleep disturbance is associated with impairment in cognitive and …
[HTML][HTML] Oxytocin and food intake control: Neural, behavioral, and signaling mechanisms
The neuropeptide oxytocin is produced in the paraventricular hypothalamic nucleus and the
supraoptic nucleus of the hypothalamus. In addition to its extensively studied influence on …
supraoptic nucleus of the hypothalamus. In addition to its extensively studied influence on …
[HTML][HTML] Ghrelin and glucagon-like peptide-1: a gut-brain axis battle for food reward
L Decarie-Spain, SE Kanoski - Nutrients, 2021 - mdpi.com
Eating behaviors are influenced by the reinforcing properties of foods that can favor
decisions driven by reward incentives over metabolic needs. These food reward-motivated …
decisions driven by reward incentives over metabolic needs. These food reward-motivated …
Melanin-concentrating hormone and food intake control: Sites of action, peptide interactions, and appetition
Given the increased prevalence of obesity and its associated comorbidities, understanding
the mechanisms through which the brain regulates energy balance is of critical importance …
the mechanisms through which the brain regulates energy balance is of critical importance …