Retinitis Pigmentosa (RP) is a hereditary retinopathy that affects about 2.5 million people
worldwide. It is characterized with progressive loss of rods and cones and causes severe …

Retinitis pigmentosa (RP) is the most common cause of inherited blindness and is
characterised by the progressive loss of retinal photoreceptors. However, RP is a highly …

Inherited mutations in the rod visual pigment, rhodopsin, cause the degenerative blinding
condition, retinitis pigmentosa (RP). Over 150 different mutations in rhodopsin have been …

Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid that has
been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of …

Diseases that affect the eye, including photoreceptor degeneration, diabetic retinopathy, and
glaucoma, affect 11.8 million people in the US, resulting in vision loss and blindness. Loss of …

Primary cilia were the largely neglected nonmotile counterparts of their better-known cousin,
the motile cilia. For years these nonmotile cilia were considered evolutionary remnants of …

Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid
(UDCA), a US Food and Drug Administration—approved hydrophilic bile acid for the …

Microglia have been implicated in many degenerative eye disorders, including retinitis
pigmentosa, age-related macular degeneration, glaucoma, diabetic retinopathy, uveitis, and …

Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …