GH Ong, BSX Lian, T Kawasaki… - Frontiers in cellular and …, 2021 - frontiersin.org
Adjuvants are used to maximize the potency of vaccines by enhancing immune reactions. Components of adjuvants include pathogen-associated molecular patterns (PAMPs) and …
D Forgacs, H Jang, RB Abreu, HB Hanley… - Frontiers in …, 2021 - frontiersin.org
As the COVID-19 pandemic continues, the authorization of vaccines for emergency use has been crucial in slowing down the rate of infection and transmission of the SARS-CoV-2 virus …
AP Tkachuk, EN Bykonia, LI Popova, DA Kleymenov… - Vaccines, 2020 - mdpi.com
GamTBvac is a candidate tuberculosis vaccine with two fusion proteins, containing Ag85a, ESAT6, CFP10, and a dextran-binding domain (DBD). Phase II of a double-blind …
DV Vasina, DA Kleymenov, VA Manuylov… - Vaccines, 2019 - mdpi.com
Tuberculosis is known to be the biggest global health problem, causing the most deaths by a single infectious agent. Vaccine-development efforts are extremely important. This paper …
S Khoshnood, M Heidary, M Haeili, M Drancourt… - International journal of …, 2018 - Elsevier
Tuberculosis (TB) is now among the top ten causes of mortality worldwide being resulted in 1.7 million deaths including 0.4 million among people with HIV in 2016. The Bacille …
Tuberculosis (TB) caused by Mycobacterium tuberculosis infection is responsible for the most deaths by a single infectious agent worldwide, with 1.6 million deaths in 2017 alone …
There is an urgent need for the development of vaccine thermostabilisation methodologies as the maintenance of a continuous and reliable cold chain remains a major hurdle to the …
Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a deadly infectious disease. The thin pipeline of new drugs for TB, the ineffectiveness in adults of the only …
HS Clemmensen, NPH Knudsen, R Billeskov… - Frontiers in …, 2020 - frontiersin.org
In most cases, Mycobacterium tuberculosis (Mtb) causes life-long chronic infections, which poses unique challenges for the immune system. Most of the current tuberculosis (TB) …