Endometriosis and nuclear receptors

BD Yilmaz, SE Bulun - Human reproduction update, 2019 - academic.oup.com
BACKGROUND Endometriosis is recognized as a steroid-dependent disorder; however, the
precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling …

[HTML][HTML] New developments in the medical treatment of endometriosis

MA Bedaiwy, S Alfaraj, P Yong, R Casper - Fertility and sterility, 2017 - Elsevier
Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are
surgical and hormonal but have limitations, including the risk of recurrence, side effects …

Medical management of endometriosis

S Rafique, AH Decherney - Clinical obstetrics and gynecology, 2017 - journals.lww.com
Endometriosis is a chronic medical condition that affects around 6% to 10% of reproductive
age women. Pelvic pain, dysmenorrhea, and infertility are the most common presenting …

[HTML][HTML] Inhalation treatment of primary lung cancer using liposomal curcumin dry powder inhalers

T Zhang, Y Chen, Y Ge, Y Hu, M Li, Y Jin - Acta Pharmaceutica Sinica B, 2018 - Elsevier
Lung cancer is the leading cause of cancer-related deaths. Traditional chemotherapy
causes serious toxicity due to the wide bodily distribution of these drugs. Curcumin is a …

Selective progesterone receptor modulators—mechanisms and therapeutic utility

MS Islam, S Afrin, SI Jones, J Segars - Endocrine Reviews, 2020 - academic.oup.com
Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

New therapeutics in endometriosis: a review of hormonal, non-hormonal, and non-coding RNA treatments

G Brichant, I Laraki, L Henry, C Munaut… - International journal of …, 2021 - mdpi.com
Endometriosis is defined as endometrial-like tissue outside the uterine cavity. It is a chronic
inflammatory estrogen-dependent disease causing pain and infertility in about 10% of …

Thymoquinone‐induced antitumor and apoptosis in human lung adenocarcinoma cells

S Samarghandian, M Azimi‐Nezhad… - Journal of cellular …, 2019 - Wiley Online Library
Background Lung cancer has been associated with the highest cancer‐associated mortality
rate in the world. Chemotherapeutic management of cancer necessitates introducing new …

Investigational drugs for the treatment of endometriosis, an update on recent developments

F Barra, C Scala, V Mais, S Guerriero… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: Endometriosis is a hormone-dependent benign chronic disease that requires a
chronic medical therapy. Although currently available drugs are efficacious in treating …

Efficacy, safety and recurrence of new progestins and selective progesterone receptor modulator for the treatment of endometriosis: a comparison study in mice

B Liang, L Wu, H Xu, CW Cheung, WY Fung… - Reproductive Biology …, 2018 - Springer
Background Current medical treatments for endometriosis are very limited. Progestin and
selective progesterone receptor modulators (SPRM) are developed but their efficacy, safety …

Clinical efficacy, pharmacokinetics, and safety of the available medical options in the treatment of endometriosis-related pelvic pain: a scoping review

M Mikuš, M Šprem Goldštajn, AS Laganà, F Vukorepa… - Pharmaceuticals, 2023 - mdpi.com
Background: In this scoping review, we sought to identify published studies evaluating the
drugs currently used in the treatment of endometriosis-related pelvic pain, with reflection on …