Strategic use of visible-light photoredox catalysis in natural product synthesis

SP Pitre, LE Overman - Chemical Reviews, 2021 - ACS Publications
Recent progress in the development of photocatalytic reactions promoted by visible light is
leading to a renaissance in the use of photochemistry in the construction of structurally …

Trends in applying C–H oxidation to the total synthesis of natural products

Y Qiu, S Gao - Natural product reports, 2016 - pubs.rsc.org
Covering: 2006 to 2015 C–H functionalization remains one of the frontier challenges in
organic chemistry and drives quite an active area of research. It has recently been applied in …

Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers

MA Beniddir, L Evanno, D Joseph, A Skiredj… - Natural product …, 2016 - pubs.rsc.org
Covering: up to 2016 Dictazoles and sceptrins are singular metabolites of marine origin. The
present dichotomic case study provides a comprehensive perspective on these cyclobutane …

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria

AG Tempone, P Pieper, SET Borborema… - Natural product …, 2021 - pubs.rsc.org
Covering: 2000 up to 2021 Natural products are an important resource in drug discovery,
directly or indirectly delivering numerous small molecules for potential development as …

Stereoselective Synthesis of Cyclohepta[b]indoles by Visible‐Light‐Induced [2+2]‐Cycloaddition/retro‐Mannich‐type Reactions

XP Mu, YH Li, N Zheng, JY Long, SJ Chen… - Angewandte …, 2021 - Wiley Online Library
A novel method for the concise synthesis of cyclohepta [b] indoles in high yields was
developed. The method involves a visible‐light‐induced, photocatalyzed [2+ 2] …

Chemistry and biology of the pyrrole–imidazole alkaloids

T Lindel - The Alkaloids: Chemistry and Biology, 2017 - Elsevier
More than a decade after our last review on the chemistry of the pyrrole–imidazole alkaloids,
it was time to analyze once more the developments in that field. The comprehensive article …

Pyrrole: An Essential Framework in the Development of Therapeutic Agents and Insightful Analysis of Structure‐Active Relationships

B Sahu, R Sahu, B Gidwani, A Mishra - ChemistrySelect, 2024 - Wiley Online Library
Pyrrole is a heterocyclic structure with diverse pharmacophores, enabling the creation of an
extensive lead molecule library. Its broad range of pharmacological profiles has concerned …

Agelanemoechine, a Dimeric Bromopyrrole Alkaloid with a Pro-Angiogenic Effect from the South China Sea Sponge Agelas nemoechinata

T Li, X Tang, X Luo, Q Wang, K Liu, Y Zhang… - Organic …, 2019 - ACS Publications
One new dimeric bromopyrrole alkaloid, agelanemoechine, with an unprecedented imidazo
[1, 5-a] azepin nucleus together with one known dimeric bromopyrrole alkaloid sceptrin were …

Marine sponge alkaloids as a source of anti-bacterial adjuvants

RJ Melander, H Liu, MD Stephens, CA Bewley… - Bioorganic & medicinal …, 2016 - Elsevier
Novel approaches that do not rely upon developing microbicidal compounds are sorely
needed to combat multidrug resistant (MDR) bacteria. The potential of marine secondary …

Appreciation of symmetry in natural product synthesis

WJ Bai, X Wang - Natural product reports, 2017 - pubs.rsc.org
Covering: 2012 to June 2017 This review aims to show that complex natural product
synthesis can be streamlined by taking advantage of molecular symmetry. Various strategies …