microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

[HTML][HTML] The role of miRNAs in colorectal cancer progression and chemoradiotherapy

N Zhang, X Hu, Y Du, J Du - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Colorectal cancer (CRC) is known as the third most common cancer as well as the fourth
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …

Tumor angiogenesis revisited: regulators and clinical implications

R Ronca, M Benkheil, S Mitola, S Struyf… - Medicinal research …, 2017 - Wiley Online Library
Abstract Since Judah Folkman hypothesized in 1971 that angiogenesis is required for solid
tumor growth, numerous studies have been conducted to unravel the angiogenesis process …

Dissecting miRNA signature in colorectal cancer progression and metastasis

X Huang, X Zhu, Y Yu, W Zhu, L Jin, X Zhang, S Li… - Cancer letters, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common cancer and leading cause of cancer
related deaths worldwide. Despite recent advancements in surgical and molecular targeted …

MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications

AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …

[HTML][HTML] Atherosclerosis and cancer; a resemblance with far-reaching implications

JV Tapia-Vieyra, B Delgado-Coello… - Archives of medical …, 2017 - Elsevier
Atherosclerosis and cancer are chronic diseases considered two of the main causes of
death all over the world. Taking into account that both diseases are multifactorial, they share …

Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer

XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …

Regulation of tumor angiogenesis by microRNAs: State of the art

NH Goradel, N Mohammadi… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs, miRs) are small (21–25 nucleotides) endogenous and noncoding
RNAs involved in many cellular processes such as apoptosis, development, proliferation …

[HTML][HTML] Detection of circulating exosomal miR-17-5p serves as a novel non-invasive diagnostic marker for non-small cell lung cancer patients

Y Zhang, Y Zhang, Y Yin, S Li - Pathology-Research and Practice, 2019 - Elsevier
Exosome-shuttled bioactive miRNAs act as novel non-invasive biomarkers for cancer
diagnosis have received increasing attention. In this study, we aimed to investigate the …