Redox metabolism: ROS as specific molecular regulators of cell signaling and function

C Lennicke, HM Cochemé - Molecular Cell, 2021 - cell.com
Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Unfolding the interactions between endoplasmic reticulum stress and oxidative stress

G Ong, SE Logue - Antioxidants, 2023 - mdpi.com
Oxidative stress is caused by an imbalance in cellular redox state due to the accumulation of
reactive oxygen species (ROS). While homeostatic levels of ROS are important for cell …

[HTML][HTML] Happily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

A Höhn, D Weber, T Jung, C Ott, M Hugo, B Kochlik… - Redox biology, 2017 - Elsevier
Aging is a complex phenomenon and its impact is becoming more relevant due to the rising
life expectancy and because aging itself is the basis for the development of age-related …

Hsp70 in redox homeostasis

H Zhang, W Gong, S Wu, S Perrett - Cells, 2022 - mdpi.com
Cellular redox homeostasis is precisely balanced by generation and elimination of reactive
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …

[HTML][HTML] Proteostasis, oxidative stress and aging

I Korovila, M Hugo, JP Castro, D Weber, A Höhn… - Redox biology, 2017 - Elsevier
The production of reactive species is an inevitable by-product of metabolism and thus, life
itself. Since reactive species are able to damage cellular structures, especially proteins, as …

Adaptive homeostasis and the free radical theory of ageing

LCD Pomatto, KJA Davies - Free Radical Biology and Medicine, 2018 - Elsevier
Abstract The Free Radical Theory of Ageing, was first proposed by Denham Harman in the
mid-1950's, based largely on work conducted by Rebeca Gerschman and Daniel Gilbert. At …

Heat shock proteins in oxidative stress and ischemia/reperfusion injury and benefits from physical exercises: a review to the current knowledge

J Szyller, I Bil-Lula - Oxidative Medicine and Cellular Longevity, 2021 - Wiley Online Library
Heat shock proteins (HSPs) are molecular chaperones produced in response to oxidative
stress (OS). These proteins are involved in the folding of newly synthesized proteins and …

Effects of protein oxidation on the texture and water-holding of meat: A review

Y Bao, P Ertbjerg - Critical reviews in food science and nutrition, 2019 - Taylor & Francis
Protein oxidation readily occurs in postmortem muscle during storage and processing. Over
the past decade new analytical methods have been developed and new aspects of protein …

The role of declining adaptive homeostasis in ageing

LCD Pomatto, KJA Davies - The Journal of physiology, 2017 - Wiley Online Library
Adaptive homeostasis is “the transient expansion or contraction of the homeostatic range for
any given physiological parameter in response to exposure to sub‐toxic, non‐damaging …

The role of oxidative stress in anxiety disorder: cause or consequence?

AG Fedoce, F Ferreira, RG Bota… - Free radical …, 2018 - Taylor & Francis
Anxiety disorders are the most common mental illness in the USA affecting 18% of the
population. The cause (s) of anxiety disorders is/are not completely clear, and research in …