Background Identifying the phenotypic manifestations of increased genetic liability for
depression (MDD) and bipolar disorder (BD) can enhance understanding of their aetiology …

Schizophrenia is currently classified as a psychotic disorder. This article posits that this
emphasis on psychosis is a conceptual fallacy that has greatly contributed to the lack of …

Lithium is the first choice drug for the long-term prophylaxis of depressive and manic
episodes in bipolar disorder (BD). Both experimental and clinical studies show either …

Background Schizophrenia and bipolar disorder share genetic liability, and some structural
brain abnormalities are common to both conditions. First-degree relatives of patients with …

BackgroundSchizophrenia is associated with lower intelligence and poor educational
performance relative to the general population. This is, to a lesser degree, also found in first …

BackgroundPoor educational achievement is associated with a range of psychiatric
disorders. Several studies suggest that this underperformance is due to cognitive deficits …

First‐degree relatives of patients diagnosed with schizophrenia (SZ‐FDRs) show similar
patterns of brain abnormalities and cognitive alterations to patients, albeit with smaller effect …

Objective To investigate whether child mental health problems prospectively associate with
IQ‐achievement discrepancy (ie, academic under‐and over‐achievement) in emerging …

Objective: To assess change in employment status in patients with bipolar disorder in
comparison with non–mentally ill controls from 1 year before bipolar incidence to 10 years …

Abstract Knowledge on how genetic risk for bipolar disorder manifests in developmental,
emotional or behavioral traits during childhood is lacking. This issue is important to address …