In vitro cytotoxicity of antiresorptive and antiangiogenic compounds on oral tissues contributing to MRONJ: systematic review
RH Guirguis, LP Tan, RM Hicks, A Hasan, TD Duong… - Biomolecules, 2023 - mdpi.com
Background: Invasive dental treatment in patients exposed to antiresorptive and
antiangiogenic drugs can cause medication-related osteonecrosis of the jaw (MRONJ) …
antiangiogenic drugs can cause medication-related osteonecrosis of the jaw (MRONJ) …
Bisphosphonate-related osteonecrosis of the jaw: a mechanobiology perspective
EL George, YL Lin, MM Saunders - Bone Reports, 2018 - Elsevier
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a dramatic disintegration of the
jaw that affects patients treated with bisphosphonates (BPs) for diseases characterized by …
jaw that affects patients treated with bisphosphonates (BPs) for diseases characterized by …
[HTML][HTML] Bisphosphonate modulation of the gene expression of different markers involved in osteoblast physiology: possible implications in bisphosphonate-related …
FJ Manzano-Moreno, J Ramos-Torrecillas… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
The aim of the present study was to elucidate the role of osteoblasts in bisphosphonates-
related osteonecrosis of the jaw (BRONJ). The specific objective was to evaluate the effect …
related osteonecrosis of the jaw (BRONJ). The specific objective was to evaluate the effect …
High molecular weight hyaluronic acid regulates P. gingivalis–induced inflammation and migration in human gingival fibroblasts via MAPK and NF-κB signaling …
M Chen, L Li, Z Wang, P Li, F Feng, X Zheng - Archives of oral biology, 2019 - Elsevier
Chronic periodontitis is associated with Porphyromonas gingivalis (P. gingivalis) infection.
Hyaluronic Acid (HA), a critical component of the extracellular matrix, exhibits anti …
Hyaluronic Acid (HA), a critical component of the extracellular matrix, exhibits anti …
The role of geranylgeraniol in managing bisphosphonate-related osteonecrosis of the jaw
Medication-related osteonecrosis of the jaw (ONJ) is a rare but significant adverse side
effect of antiresorptive drugs. Bisphosphonate-related ONJ (BRONJ) is the most prevalent …
effect of antiresorptive drugs. Bisphosphonate-related ONJ (BRONJ) is the most prevalent …
Pathogenesis of medication-related osteonecrosis of the jaw: a comparative study of in vivo and in vitro trials
H Holtmann, J Lommen, NR Kübler… - Journal of …, 2018 - journals.sagepub.com
Objective This study was performed to determine whether the results of prevailing in vivo
and in vitro studies offer a reliable model for investigation of medication-related …
and in vitro studies offer a reliable model for investigation of medication-related …
MicroRNA-125a-5p enhances the sensitivity of esophageal squamous cell carcinoma cells to cisplatin by suppressing the activation of the STAT3 signaling pathway
Y Zhao, K Ma, S Yang, X Zhang… - International …, 2018 - spandidos-publications.com
Increasing evidence has demonstrated that microRNAs (miRNAs or miRs) play a variety of
roles in tumor development, progression and chemosensitivity in a wide range of tumors. In …
roles in tumor development, progression and chemosensitivity in a wide range of tumors. In …
Geranylgeraniol restores zoledronic acid-induced efferocytosis inhibition in bisphosphonate-related osteonecrosis of the jaw
X Chen, W Zhu, R Xu, X Shen, Y Fu, J Cheng… - Frontiers in cell and …, 2021 - frontiersin.org
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe side effect of long-
term administration of bisphosphonates such as zoledronic acid (ZA), but its pathogenesis …
term administration of bisphosphonates such as zoledronic acid (ZA), but its pathogenesis …
Zoledronic acid, bevacizumab and dexamethasone-induced apoptosis, mitochondrial oxidative stress, and calcium signaling are decreased in human osteoblast-like …
Increased intracellular free calcium ion (Ca 2+) concentration induces excessive oxidative
stress and apoptosis. Medical procedures such as zoledronic acid (Zol), bevacizumab (Bev) …
stress and apoptosis. Medical procedures such as zoledronic acid (Zol), bevacizumab (Bev) …
Beneficial effect of dietary geranylgeraniol on glucose homeostasis and bone microstructure in obese mice is associated with suppression of proinflammation and …
Geranylgeraniol (GGOH) is found in edible oils such as olive, linseed, and sunflower oils,
which have favorable metabolic effects. However, it is unknown whether these physiological …
which have favorable metabolic effects. However, it is unknown whether these physiological …