Breast cancer is one of the leading causes of mortality in females. Over the past decades,
intensive efforts have been made to uncover the pathogenesis of breast cancer. Interleukin …

Abstract Interleukin-6 (IL-6) is a proinflammatory cytokine with a critical role in immune
regulation and treatment of many diseases, including breast cancer. Herein, we developed a …

While preclinical studies consistently implicate FGFR-signalling in breast cancer (BC)
progression, clinical evidence fails to support these findings. It may be that the clinical …

Despite significant therapeutic advances in recent years, treatment of metastatic prostate
cancer (PCa) remains palliative, owing to the inevitable occurrence of drug resistance …

Background Tumor cell repopulation after radiotherapy is a major cause for the tumor
radioresistance and recurrence. This study aims to investigate the underlying mechanism of …

Recurrence and poorly differentiated (grade 3 and above) and atypical cell type endometrial
cancer (EC) have poor prognosis outcome. The mechanisms and characteristics of …

Background In cancer patients, an interleukin (IL)-8 gene variant that leads to higher
production of IL-8, is associated with lower risk of depressive symptoms. In non-cancer …

Sarcodon imbricatus (S. imbricatus), a well-known edible mushroom, is one of the most
commonly consumed wild mushrooms in China because of its nutritional value. Previous …

The microenvironment of tumors is characterized by structural changes in the fibronectin
matrix, which include increased deposition of the EDA isoform of fibronectin and the …

Background Although EGFR-tyrosine kinase inhibitors (EGFR-TKIs) are the standard
treatment for patients with EGFR-mutant non-small-cell lung cancer (NSCLC), responses …