Abstract PDCD5 (programmed cell death 5) is an apoptosis related gene cloned in 1999
from a human leukemic cell line. PDCD5 protein containing 125 amino acid (aa) residues …

Summary Aims Programmed Cell Death 5 (PDCD 5) is a protein that accelerates apoptosis
in different types of cells in response to various stimuli and is down‐regulated in many …

SUMMARY Mediator 17 (MED17) is a subunit of the Mediator complex that regulates
transcription initiation in eukaryotic organisms. In yeast and humans, MED17 also …

Maintenance of FOXP3 protein expression is crucial for differentiation and maturation of
regulatory T (Treg) cells, which play important roles in immune homeostasis and immune …

The tumor suppressor p53 plays a central role in cell fate decisions after DNA damage.
Programmed Cell Death 5 (PDCD5) interacts with the p53 pathway to promote cell …

The tumor suppressor p53 is activated in response to cellular stresses. The transcription
factor p53 can activate the expression of numerous genes leading to cell cycle arrest …

DNA damage responses have evolved to sense and react to DNA damage; the induction of
DNA repair mechanisms can lead to genomic restoration or, if the damaged DNA cannot be …

A potentially viable approach for treating late-stage prostate cancer is gene therapy.
Successful gene therapy requires safe and efficient delivery systems. In this study, we report …

The dynamics of tumor suppressor p53 is closely related to cell fate decisions in responses
to various stress signals, especially p53 oscillation. In this paper, phase transition of p53 …

Background In multiple sclerosis (MS) and its widely used animal model, experimental
autoimmune encephalomyelitis (EAE), autoreactive T cells contribute importantly to central …