Agmatine (decarboxylated L-arginine): physiological role and therapeutic potential
GJ Molderings, B Haenisch - Pharmacology & therapeutics, 2012 - Elsevier
Agmatine, a cationic amine formed by decarboxylation of l-arginine by the mitochondrial
enzyme arginine decarboxylase (ADC), is widely but unevenly distributed in mammalian …
enzyme arginine decarboxylase (ADC), is widely but unevenly distributed in mammalian …
Vascular regulation by the L-arginine metabolites, nitric oxide and agmatine
SAV Raghavan, M Dikshit - Pharmacological research, 2004 - Elsevier
Research on the biochemistry and physiology of l-arginine has remained an attractive area
for scientists over the last 100 years due to its diverse physiological functions in mammals …
for scientists over the last 100 years due to its diverse physiological functions in mammals …
Arginine deprivation, growth inhibition and tumour cell death: 2. Enzymatic degradation of arginine in normal and malignant cell cultures
R Philip, E Campbell, DN Wheatley - British journal of cancer, 2003 - nature.com
Arginase added to culture medium reduced arginine to negligible levels within∼ 6 h, and
enzyme activity persisted relatively undiminished for at least 3 days. Human and bovine …
enzyme activity persisted relatively undiminished for at least 3 days. Human and bovine …
Anticonvulsive effect of agmatine in mice
RB Su, XL Wei, JQ Zheng, Y Liu, XQ Lu, J Li - … Biochemistry and Behavior, 2004 - Elsevier
The present study was designed to examine the effect of agmatine, the decarboxylated
product of l-arginine by l-arginine decarboxylase, on convulsion in the mouse maximal …
product of l-arginine by l-arginine decarboxylase, on convulsion in the mouse maximal …
Agmatine modulates spontaneous activity in neurons of the rat medial habenular complex—a relevant mechanism in the pathophysiology and treatment of depression …
T Weiss, R Bernard, HG Bernstein, RW Veh… - Translational …, 2018 - nature.com
The dorsal diencephalic conduction system connects limbic forebrain structures to
monaminergic mesencephalic nuclei via a distinct relay station, the habenular complexes …
monaminergic mesencephalic nuclei via a distinct relay station, the habenular complexes …
Pharmacological effects of Eugenia punicifolia (Myrtaceae) in cholinergic nicotinic neurotransmission
MS Grangeiro, AP Calheiros-Lima, MF Martins… - Journal of …, 2006 - Elsevier
The effects of the aqueous crude extract (5%) of Eugenia punicifolia on cholinergic nicotinic
neurotransmission were investigated. Actions of aqueous crude extract over the inhibitory …
neurotransmission were investigated. Actions of aqueous crude extract over the inhibitory …
Alpha2-adrenoceptors in adrenomedullary chromaffin cells: functional role and pathophysiological implications
AR Artalejo, LA Olivos-Oré - Pflügers Archiv-European Journal of …, 2018 - Springer
Chromaffin cells from the adrenal medulla participate in stress responses by releasing
catecholamines into the bloodstream. Main control of adrenal catecholamine secretion is …
catecholamines into the bloodstream. Main control of adrenal catecholamine secretion is …
[PDF][PDF] Agmatine modulation of noradrenergic neurotransmission in isolated rat blood vessels
J Török, A Zemančíková - Chin J Physiol, 2016 - cps.org.tw
Agmatine, a vasoactive metabolite of L-arginine, is widely distributed in mammalian tissues
including blood vessels. Agmatine binding to imidazoline and α2-adrenoceptors induces a …
including blood vessels. Agmatine binding to imidazoline and α2-adrenoceptors induces a …
Augmentation of catecholamine release elicited by an Eugenia punicifolia extract in chromaffin cells
Plant extracts of Eugenia punicifolia (Kunth) DC., Myrtaceae, are used in Amazon region of
Brazil to treat diarrhea and stomach disturbances, and as hypoglycemic medicine. We have …
Brazil to treat diarrhea and stomach disturbances, and as hypoglycemic medicine. We have …