Circadian rhythms of the hypothalamus: from function to physiology

R Van Drunen, K Eckel-Mahan - Clocks & sleep, 2021 - mdpi.com
The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …

Astrocyte clocks and glucose homeostasis

O Barca-Mayo, M López - Frontiers in Endocrinology, 2021 - frontiersin.org
The endogenous timekeeping system evolved to anticipate the time of the day through the
24 hours cycle of the Earth's rotation. In mammals, the circadian clock governs rhythmic …

Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice

CM Gallardo, M Darvas, M Oviatt, CH Chang… - Elife, 2014 - elifesciences.org
Daily rhythms of food anticipatory activity (FAA) are regulated independently of the
suprachiasmatic nucleus, which mediates entrainment of rhythms to light, but the neural …

Synchronization of the circadian clock by time-restricted feeding with progressive increasing calorie intake. Resemblances and differences regarding a sustained …

AC García-Gaytán, M Miranda-Anaya, I Turrubiate… - Scientific Reports, 2020 - nature.com
Circadian rhythms are the product of the interaction of molecular clocks and environmental
signals, such as light-dark cycles and eating-fasting cycles. Several studies have …

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric‐restricted ageing mice

K van Norren, F Rusli, M van Dijk, C Lute… - Journal of cachexia …, 2015 - Wiley Online Library
Background In rodent models, caloric restriction (CR) with maintenance of adequate
micronutrient supply has been reported to increase lifespan and to reduce age‐induced …

Studying food entrainment: Models, methods, and musings

JR Trzeciak, AD Steele - Frontiers in Nutrition, 2022 - frontiersin.org
The ability to tell time relative to predictable feeding opportunities has a long history of
research, going back more than 100 years with behavioral observations of honeybees and …

Circadian mechanisms of food anticipatory rhythms in rats fed once or twice daily: clock gene and endocrine correlates

DF Patton, AM Katsuyama, I Pavlovski, M Michalik… - PloS one, 2014 - journals.plos.org
Circadian clocks in many brain regions and peripheral tissues are entrained by the daily
rhythm of food intake. Clocks in one or more of these locations generate a daily rhythm of …

Type 1 dopamine receptor (D1R)-independent circadian food anticipatory activity in mice

DR Assali, M Sidikpramana, AP Villa, J Falkenstein… - PLoS …, 2021 - journals.plos.org
Circadian rhythms are entrained by light and influenced by non-photic stimuli, such as
feeding. The activity preceding scheduled mealtimes, food anticipatory activity (FAA), is …

The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation

B Podyma, DA Johnson, L Sipe, TP Remcho, K Battin… - Elife, 2020 - elifesciences.org
Networks of neurons control feeding and activity patterns by integrating internal metabolic
signals of energy balance with external environmental cues such as time-of-day. Proper …

A subpopulation of agouti-related peptide neurons exciting corticotropin-releasing hormone axon terminals in median eminence led to hypothalamic-pituitary-adrenal …

R Yesmin, M Watanabe, AS Sinha… - Frontiers in Molecular …, 2022 - frontiersin.org
The excitatory action of gamma-aminobutyric-acid (GABA) in the median-eminence (ME) led
to the steady-state release of corticotropin-releasing hormone (CRH) from CRH axon …