[HTML][HTML] Natural products as pharmacological modulators of mitochondrial dysfunctions for the treatment of diabetes and its complications: An update since 2010

QR Lin, LQ Jia, M Lei, D Gao, N Zhang, L Sha… - Pharmacological …, 2024 - Elsevier
Diabetes, characterized as a well-known chronic metabolic syndrome, with its associated
complications pose a substantial and escalating health and healthcare challenge on a …

Cardiovascular protective effects of cinnamic acid as a natural phenolic acid: a review

L Safaeian, M Asghari-Varzaneh, SS Alavi… - … of Physiology and …, 2024 - Taylor & Francis
Phenolic acids derived from plants have beneficial effects on cardiovascular diseases
(CVD). Cinnamic acid (CA) is a crucial phenolic acid that can form numerous …

Exploring cardiac impact of oral nicotine exposure in a transplantable Neoplasm Mice Model: Insights from biochemical analysis, morphometry, and molecular docking …

AAR Mohamed, GG Moustafa, KM El Bohy, TM Saber… - Toxicology, 2023 - Elsevier
Nicotine-induced cardiac tissue damage is a concern for cancer patients, but the exact
pathogenesis from nicotine oral exposure is unclear. This study was designed to investigate …

[HTML][HTML] A Review of Cinnamic Acid's Skeleton Modification: Features for Antibacterial-Agent-Guided Derivatives

RM Annuur, D Triana, T Ernawati, Y Murai, M Aswad… - Molecules, 2024 - mdpi.com
Antimicrobial resistance has emerged as a significant danger to global health, and the need
for more effective antimicrobial resistance (AMR) control has been highlighted. Cinnamic …

[HTML][HTML] Downregulated DKK2 may serve as a molecular mechanism of high-fat diet-induced myocardial injury via Wnt/β-catenin pathway

Y Wang, D Chen, Y Pu, J Shi, C Yi, J Chen, G Yang… - Life Sciences, 2025 - Elsevier
Objective High-fat diet could induce structural and functional disorders of the heart, but the
underlying mechanism remains elusive. This study aimed to explore related mechanism of …

Design, Synthesis, Molecular Docking and Cytotoxicity of Stilbene-arylcinnamide Hybrids on A549 Lung Cancer Cells

NSM Zaki, NNSN Mohamad Kamal… - Current Organic …, 2023 - ingentaconnect.com
A new series of stilbene-arylcinnamide hybrids have been designed and synthesized with
various substituents. These compounds were characterized by FTIR, 1D-and 2D-NMR as …

[HTML][HTML] Study of Host-Guest Interaction and In Vitro Neuroprotective Potential of Cinnamic Acid/Randomly Methylated β-Cyclodextrin Inclusion Complex

F De Gaetano, L Leggio, C Celesti, F Genovese… - International Journal of …, 2024 - mdpi.com
Cinnamic acid (CA) has many beneficial effects on human health. However, its poor water
solubility (0.23 g/L, at 25° C) is responsible for its poor bioavailability. This drawback …

Targeting Matrix Metalloproteinase‐3 for Dental Caries Prevention Using Herbal Isolates: MMP3 Inhibition by Cinnamic Acids

M Salman, B Asgartooran… - International Journal of …, 2024 - Wiley Online Library
Objectives: Dental caries, a prevalent infectious disease affecting teeth, ranks highest
among 328 diseases, according to a 2017 Lancet study. In demineralized human dentin …

[HTML][HTML] 1,2-Dicinnamoyl-sn-glycero-3-phosphocholine Improves Insulin Sensitivity and Upregulates mtDNA-Encoded Genes in Insulin-Resistant 3T3-L1 Adipocytes …

A Cierzniak, A Gliszczyńska, M Małodobra-Mazur - Nutrients, 2024 - mdpi.com
Background: Insulin resistance is a condition characterized by a reduced biological
response to insulin. It is one of the most common metabolic diseases in modern civilization …

Cinnamon for Metabolic Diseases and Their Cardiovascular and Hepatic Complications: A Mechanistic Review

J Wu, W Jia, D Min, G Yang - The American Journal of Chinese …, 2024 - World Scientific
Cinnamon is one of the world's oldest and most popular spices, and is derived from the inner
bark of several tree species from the genus Cinnamomum. During the last two decades …