Childhood brain tumors are the most common pediatric solid tumor and include several
histologic subtypes. Although progress has been made in improving survival rates for some …

Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of
children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in …

Atypical teratoid/rhabdoid tumors (ATRTs) typically arise in the central nervous system
(CNS) of children under 3 years of age. Despite intensive multimodal therapy (surgery …

Pediatric neuro-oncology has undergone an exciting and dramatic transformation during the
past 5 years. This article summarizes data from collaborative group and institutional trials …

Background Controversy exists as to what may be defined as standard of care (including
markers for stratification) for patients with atypical teratoid/rhabdoid tumors (ATRTs). The …

Background Rhabdoid brain tumours, also called atypical teratoid rhabdoid tumours, are
lethal childhood cancers with characteristic genetic alterations of SMARCB1/hSNF5. Lack of …

Atypical teratoid rhabdoid tumors (ATRTs) are rare central nervous system tumors that
comprise approximately 1–2% of all pediatric brain tumors; however, in patients less than 3 …

Recent years have witnessed a shift to more objective and biologically-driven methods for
central nervous system (CNS) tumor classification. The 2016 world health organization …

BACKGROUND: Atypical teratoid rhabdoid tumor (ATRT) is a rare central nervous system
malignancy with a poor prognosis that affects mostly young children. Although radiotherapy …

Purpose: Report relevance of molecular groups to clinicopathologic features, germline
SMARCB1/SMARCA4 alterations (GLA), and survival of children with atypical teratoid …