Histone deacetylases (HDACs) are evolutionary conserved enzymes which operate by
removing acetyl groups from histones and other protein regulatory factors, with functional …

Histone deacetylase inhibitors (HDACis) have now emerged as a powerful new class of
small-molecule therapeutics acting through the regulation of the acetylation states of histone …

Histone deacetylases (HDACs) are epigenetic enzymes that play a central role in gene
regulation and are sensitive to the metabolic state of the cell. The cross talk between …

Abstract Type 1 diabetes (T1D) also known as juvenile diabetes is a chronic autoimmune
disorder that precipitates in genetically susceptible individuals by environmental factors …

Type 2 diabetes (T2D) is a major chronic healthcare concern worldwide. Emerging evidence
suggests that a histone-modification-mediated epigenetic mechanism underlies T2D …

Context: In vitro and in vivo research has shown that curcumin can alleviate diabetes and
the relevant complications. Objective: To investigate the effect of curcumin on gestational …

Diabetes mellitus (DM) is one of the principal manifestations of metabolic syndrome and its
prevalence with modern lifestyle is increasing incessantly. Chronic hyperglycemia can …

The contribution of epigenetic mechanisms in diabetes mellitus (DM), β-cell reprogramming
and its complications is an emerging concept. Recent evidence suggests that there is a link …

Metabolic adaptation to changing dietary conditions is critical to maintain homeostasis of the
internal milieu. In metazoans, this adaptation is achieved by a combination of tissue …

Histone deacetylases (HDACs) are involved in tumorigenesis and progression, however,
their role in diffuse large B-cell lymphoma (DLBCL) is not well understood. In this study, we …