[HTML][HTML] Methods and biomarkers for early detection, prediction, and diagnosis of colorectal cancer

Y Zhang, Y Wang, B Zhang, P Li, Y Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most common digestive diseases worldwide. It has
steadily ascended to the top three cancers in terms of incidence and mortality. The primary …

In-depth quantitative proteomics analysis revealed C1GALT1 depletion in ECC-1 cells mimics an aggressive endometrial cancer phenotype observed in cancer …

A Montero-Calle, Á López-Janeiro, ML Mendes… - Cellular Oncology, 2023 - Springer
Background Endometrial cancer (EC) is the most common cancer of the female reproductive
organs. Despite the good overall prognosis of most low-grade ECs, FIGO I and FIGO II …

Metabolic reprogramming helps to define different metastatic tropisms in colorectal cancer

A Montero-Calle, M Gómez de Cedrón… - Frontiers in …, 2022 - frontiersin.org
Approximately 25% of colorectal cancer (CRC) patients experience systemic metastases,
with the most frequent target organs being the liver and lung. Metabolic reprogramming has …

In-Depth Proteomic Analysis of Paraffin-Embedded Tissue Samples from Colorectal Cancer Patients Revealed TXNDC17 and SLC8A1 as Key Proteins Associated …

A Montero-Calle, M Garranzo-Asensio… - Journal of Proteome …, 2024 - ACS Publications
A deeper understanding of colorectal cancer (CRC) biology would help to identify specific
early diagnostic markers. Here, we conducted quantitative proteomics on FFPE healthy …

Application of two-dimensional difference gel electrophoresis to identify protein changes between center, margin, and adjacent non-tumor tissues obtained from non …

A Ciereszko, MA Dietrich, M Słowińska, J Nynca… - Plos one, 2022 - journals.plos.org
Lung cancer is responsible for the most cancer-related mortality worldwide and the
mechanism of its development is poorly understood. Proteomics has become a powerful tool …

Proteomics analyses of small extracellular vesicles of aqueous humor: identification and validation of GAS6 and SPP1 as glaucoma markers

R Rejas-González, A Montero-Calle… - International journal of …, 2024 - mdpi.com
Cataracts and glaucoma account for a high percentage of vision loss and blindness
worldwide. Small extracellular vesicles (sEVs) are released into different body fluids …

High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer

SB Ye, YK Cheng, PS Li, L Zhang, LH Zhang… - NPJ Precision …, 2023 - nature.com
Adjuvant chemotherapy (ACT) is usually used to reduce the risk of disease relapse and
improve survival for stage II/III colorectal cancer (CRC). However, only a subset of patients …

Identification of TRAPPC9 and BAIAP2 Gene Polymorphisms and Their Association With Fat Deposition-Related Traits in Hu Sheep

P Cui, W Wang, D Zhang, C Li, Y Huang… - Frontiers in Veterinary …, 2022 - frontiersin.org
Fat deposition is an important economic trait that is closely related to feed efficiency and
carcass performance in livestock. In this study, the fat deposition-related traits of 1,293 Hu …

A novel pipeline employing deep multi-attention channels network for the autonomous detection of metastasizing cells through fluorescence microscopy

M Mamalakis, SC Macfarlane, SV Notley… - Computers in Biology …, 2024 - Elsevier
Metastasis driven by cancer cell migration is the leading cause of cancer-related deaths. It
involves significant changes in the organization of the cytoskeleton, which includes the actin …

Functional Proteomics Characterization of the Role of SPRYD7 in Colorectal Cancer Progression and Metastasis

A Montero-Calle, S Jiménez de Ocaña… - Cells, 2023 - mdpi.com
SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial
proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer …