Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Ferroptosis is a new mode of cell death different from cell necrosis, autophagy, apoptosis,
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …

As an iron-dependent mode of programmed cell death induced by lipid peroxidation,
ferroptosis plays an important role in cancer therapy. The metabolic reprogramming in tumor …

Vasculogenic mimicry (VM) is a blood supply system independent of endothelial vessels in
tumor cells from different origins. It reflects the plasticity of aggressive tumor cells that …

Background: Cancer has been considered to be a global health concern due to the impact of
disease on the quality of life. The continual increase of cancer cases as well as the …

Tumor cell vasculogenic mimicry (VM), also dubbed vascular mimicry, describes the
plasticity of aggressive cancer cells forming de novo vascular networks and is associated …

Enhanced neovasculogenesis, especially vasculogenic mimicry (VM), contributes to the
development of triple-negative breast cancer (TNBC). Breast tumor-initiating cells (BTICs) …

Rho-associated coiled-coil-containing protein kinase (ROCK)/Lin11, Isl-1 and Mec-3 kinase
(LIMK)/cofilin-signaling cascades are stimulated by receptor tyrosine kinases, G protein …

Vasculogenic mimicry (VM) describes the process utilized by highly aggressive cancer cells
to generate vascular-like structures without the presence of endothelial cells. VM has been …

The difficulty and poor prognosis of malignant tumor have always been a difficult problem to
be solved. The internal components of solid tumor are complex, including tumor cells …