Digital nerve injury: assessment and treatment

MB Weber, JE Isaacs - JAAOS-Journal of the American Academy …, 2023 - journals.lww.com
Undertreated digital nerve injuries may result in sensory deficits and pain. Early recognition
and treatment will optimize outcomes, and providers should maintain a high index of …

Evaluation of processed nerve allograft in peripheral nerve surgery: a systematic review and critical appraisal

D Frostadottir, A Chemnitz, LJJ Ot, J Holst… - … Surgery–Global Open, 2023 - journals.lww.com
Background: Peripheral nerve injuries cause substantial problems when not treated
properly. A specific problem is reconstruction of nerve defects, which can be treated in …

[HTML][HTML] A multicenter prospective randomized comparison of conduits versus decellularized nerve allograft for digital nerve repairs

J Isaacs, JA Nydick, KR Means, GA Merrell… - The Journal of Hand …, 2023 - Elsevier
Purpose While there are advantages and disadvantages to both processed nerve allografts
(PNA) and conduits, a large, well-controlled prospective study is needed to compare the …

[HTML][HTML] Intraneural fibrosis and loss of microvascular architecture—Key findings investigating failed human nerve allografts

I Zucal, D Mihic-Probst, AL Pignet, M Calcagni… - Annals of Anatomy …, 2022 - Elsevier
Background Processed nerve allografts are increasingly used in clinical nerve
reconstruction with promising results. However, allograft failure has been reported, leading …

Gold and cobalt oxide nanoparticles modified poly-propylene poly-ethylene glycol membranes in poly (ε-Caprolactone) conduits enhance nerve regeneration in the …

DB Hazer Rosberg, B Hazer, L Stenberg… - International Journal of …, 2021 - mdpi.com
Reconstruction of nerve defects is a clinical challenge. Autologous nerve grafts as the gold
standard treatment may result in an incomplete restoration of extremity function. Biosynthetic …

[HTML][HTML] Development and In Vitro Evaluation of Biomimetic Injectable Hydrogels from Decellularized Human Nerves for Central Nervous System Regeneration

G Agarwal, K Moes, CE Schmidt - Materials Today Bio, 2025 - Elsevier
Injuries to the central nervous system (CNS) often lead to persistent inflammation and limited
regeneration. This study developed a clinically relevant injectable hydrogel derived from …

Nerve Allografts: Current Utility and Future Directions

JE Isaacs, JJ Drinane - Hand Clinics, 2024 - hand.theclinics.com
Introduced to the medical community in 2007, processed nerve allograft (PNA) is now
commercially available throughout the United States and Canada and many countries …

Digital nerve reconstruction

TR Acott - Orthopedic Clinics, 2022 - orthopedic.theclinics.com
If primary end-to-end neurorrhaphy is not possible because of a nerve gap after adequate
debridement of nerve ends, a nerve reconstruction should be performed. Options include …

Digital nerve reconstruction with a new composite silk fibroin nerve conduit

O Politikou, FS Frueh, M Greminger… - Journal of the …, 2025 - Wiley Online Library
Abstract Background and Aims Peripheral nerve injuries often require bridging when direct
repair is not feasible. Nerve autografts are the gold standard, but they can lead to donor site …

Hot Topics in Hand and Wrist Surgery

TA Doering, BM Mauck… - Orthopedic …, 2021 - orthopedic.theclinics.com
Volar locked plating for distal radial fractures continues to demonstrate reliably good
outcomes when compared with alternative techniques, including casting, but not necessarily …