Viral immune evasion: a masterpiece of evolution
MT Vossen, EM Westerhout, C Söderberg-Nauclér… - Immunogenetics, 2002 - Springer
Coexistence of viruses and their hosts imposes an evolutionary pressure on both the virus
and the host immune system. On the one hand, the host has developed an immune system …
and the host immune system. On the one hand, the host has developed an immune system …
Human minor histocompatibility antigens: new concepts for marrow transplantation and adoptive immunotherapy
E Goulmy - Immunological reviews, 1997 - Wiley Online Library
Bone marrow transplantation (BMT) is the present treatment for hematological malignancies,
Two major drawbacks of allogeneic BMT are graft‐versus‐host disease (GVHD) and …
Two major drawbacks of allogeneic BMT are graft‐versus‐host disease (GVHD) and …
Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes
P Klenerman, RM Zinkernagel - Nature, 1998 - nature.com
Some viruses, including human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in
humans, and lymphocytic choriomeningitis virus (LCMV) in mice, are initially controlled by …
humans, and lymphocytic choriomeningitis virus (LCMV) in mice, are initially controlled by …
Escape of human immunodeficiency virus from immune control
AJ McMichael, RE Phillips - Annual review of immunology, 1997 - annualreviews.org
▪ Abstract Cytotoxic T lymphocytes (CTL) play a crucial role in the attempt to control infection
with human immunodeficiency virus (HIV). Variation in epitopes recognized by CTL is …
with human immunodeficiency virus (HIV). Variation in epitopes recognized by CTL is …
Association of malaria parasite population structure, HLA, and immunological antagonism
Host-parasite coevolution has been likened to a molecular arms race, with particular
parasite genes evolving to evade specific host defenses. Study of the variants of an …
parasite genes evolving to evade specific host defenses. Study of the variants of an …
[图书][B] Killer cell dynamics: mathematical and computational approaches to immunology
D Wodarz - 2007 - Springer
One of the most complicated organs of higher organisms is the immune system. The function
of the immune system is to fight off pathogenic organisms that enter and grow within the host …
of the immune system is to fight off pathogenic organisms that enter and grow within the host …
Viral escape mechanisms–escapology taught by viruses
Viruses have 'studied'immunology over millions of years of coevolution with their hosts.
During this ongoing education they have developed countless mechanisms to escape from …
During this ongoing education they have developed countless mechanisms to escape from …
Cellular immune responses against hepatitis C virus: the evidence base 2002
Hepatitis C virus (HCV) is an RNA virus which is estimated to persistently infect about 170
million people worldwide. After acute infection, there is an initial period during which long …
million people worldwide. After acute infection, there is an initial period during which long …
De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type …
Human immunodeficiency virus type 1 (HIV-1) evades CD8+ T-cell responses through
mutations within targeted epitopes, but little is known regarding its ability to generate de …
mutations within targeted epitopes, but little is known regarding its ability to generate de …
A Canarypox Vaccine Expressing Multiple Human Immunodeficiency Virus Type 1 Genes Given Alone or with Rgp120 Elicits Broad and Durable CD8+ Cytotoxic T …
TG Evans, MC Keefer, KJ Weinhold… - The Journal of …, 1999 - academic.oup.com
Induction of CD8+ cytotoxic T cells is considered one of the important correlates for the
protective efficacy of candidate human immunodeficiency virus type 1 (HIV-1) vaccines. To …
protective efficacy of candidate human immunodeficiency virus type 1 (HIV-1) vaccines. To …