Neurological, Behavioral, and Pathophysiological Characterization of the Co-Occurrence of Substance Use and HIV: A Narrative Review

L Vines, D Sotelo, N Giddens, P Manza, ND Volkow… - Brain Sciences, 2023 - mdpi.com
Combined antiretroviral therapy (cART) has greatly reduced the severity of HIV-associated
neurocognitive disorders in people living with HIV (PLWH); however, PLWH are more likely …

The global burden of cognitive impairment in people with HIV

LD Keng, A Winston, CA Sabin - Aids, 2023 - journals.lww.com
Objective: While life expectancies of people with HIV (PWH) have increased through the
successes of antiretroviral treatment, cognitive impairment remains a pressing concern …

Machine learning approaches to understand cognitive phenotypes in people with HIV

SS Mukerji, KJ Petersen, KM Pohl… - The Journal of …, 2023 - academic.oup.com
Cognitive disorders are prevalent in people with HIV (PWH) despite antiretroviral therapy.
Given the heterogeneity of cognitive disorders in PWH in the current era and evidence that …

Biopsychosocial phenotypes in people with HIV in the CHARTER cohort

B Tang, RJ Ellis, F Vaida, A Umlauf… - Brain …, 2024 - academic.oup.com
Neuropsychiatric complications such as neurocognitive impairment and depression are
common in people with HIV despite viral suppression on antiretroviral therapy, but these …

Identifying and distinguishing cognitive profiles among virally suppressed people with HIV.

EE Sundermann, R Dastgheyb, DJ Moore… - …, 2024 - psycnet.apa.org
Objective: Cognitive deficits are common among people with HIV (PWH), even when virally
suppressed. We identified cognitive profiles among virally suppressed PWH and determined …

A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation

AF League, BJ Yadav-Samudrala, R Kolagani… - Frontiers in …, 2024 - frontiersin.org
Background Human immunodeficiency virus (HIV) affects nearly 40 million people globally,
with roughly 80% of all people living with HIV receiving antiretroviral therapy. Antiretroviral …

Sex-specific associations between cerebrospinal fluid inflammatory biomarkers and cognition in antiretroviral-naïve people with HIV in rural Uganda

J Denniss, RT Veenhuis, Y Xu, L Lang, D Saylor… - Brain, Behavior, and …, 2025 - Elsevier
Globally, people with HIV (PWH) experience a broad spectrum of cognitive impairment that
can be noted both before and after initiation of antiretroviral therapy (ART). Sex differences …

Effects of acute Δ9-tetrahydrocannabinol on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male mice

BJ Yadav-Samudrala, BL Gorman, H Dodson… - Brain Research, 2024 - Elsevier
Cannabis use is highly prevalent especially among people living with HIV (PLWH).
Activation of the anti-inflammatory and neuroprotective endocannabinoid system by …

Development of a refined harmonization approach for longitudinal cognitive data in people with HIV

L Lang, LH Rubin, RM Dastgheyb, DE Vance… - Journal of Clinical …, 2025 - Elsevier
Objectives The aim of this study was to develop a refined method for harmonizing
longitudinal cognitive data across several large-scale studies in people with HIV (PWH), in …

Bridging brain and blood: a prospective view on neuroimaging-exosome correlations in HIV-associated neurocognitive disorders

H Luo, J Chen, J Liu, W Wang, C Hou, X Jiang… - Frontiers in …, 2025 - frontiersin.org
HIV-associated neurocognitive disorder (HAND) is a complex neurological complication
resulting from human immunodeficiency virus (HIV) infection, affecting about 50% of …