2000 Fleming Lecture. The origin and evolution of hepatitis viruses in humans

P Simmonds - Journal of General Virology, 2001 - microbiologyresearch.org
The spread and origins of hepatitis C virus (HCV) in human populations have been the
subject of extensive investigations, not least because of the importance this information …

Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication

Y Yu, Z Wan, JH Wang, X Yang, C Zhang - Virulence, 2022 - Taylor & Francis
ABSTRACT Human pegivirus (HPgV-1), previously known as GB virus C (GBV-C) or
hepatitis G virus (HGV), is a single-stranded positive RNA virus belonging to the genus …

Structural constraints on RNA virus evolution

P Simmonds, DB Smith - Journal of virology, 1999 - Am Soc Microbiol
The recently discovered hepatitis G virus (HGV) or GB virus C (GBV-C) is widely distributed
in human populations, and homologues such as HGV/GBV-CCPZ and GBV-A are found in a …

Reconstructing the origins of human hepatitis viruses

P Simmonds - … Transactions of the Royal Society of …, 2001 - royalsocietypublishing.org
Infections with hepatitis B and C viruses (HBV, HCV) are widespread in human populations
throughout the world, and are major causes of chronic liver disease and liver cancer. HBV …

Global prevalence of human pegivirus‐1 in healthy volunteer blood donors: a systematic review and meta‐analysis

N Yang, R Dai, X Zhang - Vox Sanguinis, 2020 - Wiley Online Library
Background and objectives The local prevalence of HPgV‐1 has been reported from
different countries worldwide, but the global prevalence of HPgV‐1 remains unknown. The …

Human pegivirus type 1 infection in Asia—A review of the literature

J Zimmerman, JT Blackard - Reviews in medical virology, 2022 - Wiley Online Library
The human pegivirus type 1 (HPgV‐1)—as known as hepatitis G virus and GB virus C—is a
common single‐stranded RNA flavivirus. Because few studies have demonstrated an …

Prevalence of GB virus C/Hepatitis G virus infection among various populations in Surabaya, Indonesia, and identification of novel groups of sequence variants

R Handajani, Soetjipto, MI Lusida… - Journal of clinical …, 2000 - Am Soc Microbiol
ABSTRACT A molecular epidemiological study was performed to investigate the prevalence
of GB virus C/hepatitis G virus (GBV-C/HGV) infection among various populations in …

Evolutionarily conserved RNA secondary structures in coding and non-coding sequences at the 3′ end of the hepatitis G virus/GB-virus C genome

NM Cuceanu, A Tuplin… - Journal of General …, 2001 - microbiologyresearch.org
Hepatitis G virus (HGV)/GB virus C (GBV-C) causes persistent, non-pathogenic infection in a
large proportion of the human population. Epidemiological and genetic evidence indicates a …

HIV-GB virus C co-infection: an overview

GL Baggio-Zappia… - Clinical chemistry and …, 2009 - degruyter.com
Abstract GB virus C (GBV-C) and hepatitis G virus (HGV) are two isolates of the same virus,
independently identified in humans in the 1990s by two research laboratories, and were …

Bayesian coalescent analysis reveals a high rate of molecular evolution in GB virus C

CM Romano, PMA Zanotto, EC Holmes - Journal of molecular evolution, 2008 - Springer
Abstract GB virus C/hepatitis G (GBV-C) is an RNA virus of the family Flaviviridae. Despite
replicating with an RNA-dependent RNA polymerase, some previous estimates of rates of …