Simple Summary Oxidative stress occurs within biological systems when free radicals,
classified as reactive oxygen species and reactive nitrogen species, are in excess. The …

Transcription factors of the forkhead box, class O (FoxO) family are important regulators of
the cellular stress response and promote the cellular antioxidant defense. On one hand …

Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

We know that blood plasma contains many proteins and also other components that bind
copper. The largest contributor to copper in the plasma is ceruloplasmin, which accounts for …

The serum concentrations of copper (Cu) and zinc (Zn) are strictly regulated by
compensatory mechanisms that act to stabilize them within certain ranges of nutritional …

Systemic lupus erythematosus (SLE) is the prototypical autoimmune disease that can affect
any organ of the body. Multiple mechanisms may contribute to the pathophysiology of …

Sažetak Iron metabolism has been intensively examined over the last decade and there are
many new players in this field which are worth to be introduced. Since its discovery many …

Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular
interest for its role in efflux of iron from cells, but has additional functions. Here we tested the …

This review discussed the relationship among copper, human, and bacteria. Copper plays
an important role in human immunity. Copper can boost human immune defense reactions …

Iron homeostasis is critical for cellular and organismal function and is tightly regulated to
prevent toxicity or anemia due to iron excess or deficiency, respectively. However …