Advancements in zebrafish applications for 21st century toxicology

GR Garcia, PD Noyes, RL Tanguay - Pharmacology & therapeutics, 2016 - Elsevier
The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …

A primer for morpholino use in zebrafish

BR Bill, AM Petzold, KJ Clark, LA Schimmenti… - Zebrafish, 2009 - liebertpub.com
Morpholino oligonucleotides are the most common anti-sense “knockdown” technique used
in zebrafish (Danio rerio). This review discusses common practices for the design …

The zebrafish (Danio rerio) as a model organism, with emphasis on applications for finfish aquaculture research

L Ribas, F Piferrer - Reviews in Aquaculture, 2014 - Wiley Online Library
The zebrafish (D anio rerio) is a freshwater teleost of the family C yprinidae that is
established as a model organism in many research fields. Here, we define the …

Lessons from morpholino-based screening in zebrafish

VM Bedell, SE Westcot, SC Ekker - Briefings in functional …, 2011 - academic.oup.com
Morpholino oligonucleotides (MOs) are an effective, gene-specific antisense knockdown
technology used in many model systems. Here we describe the application of MOs in …

An ontology approach to comparative phenomics in plants

A Oellrich, RL Walls, EKS Cannon, SB Cannon… - Plant methods, 2015 - Springer
Background Plant phenotype datasets include many different types of data, formats, and
terms from specialized vocabularies. Because these datasets were designed for different …

[HTML][HTML] Integration of prostate cancer clinical data using an ontology

H Min, FJ Manion, E Goralczyk, YN Wong… - Journal of biomedical …, 2009 - Elsevier
It is increasingly important for investigators to efficiently and effectively access, interpret, and
analyze the data from diverse biological, literature, and annotation sources in a unified way …

Current perspectives in zebrafish reverse genetics: moving forward

I Skromne, VE Prince - Developmental Dynamics, 2008 - Wiley Online Library
Use of the zebrafish as a model of vertebrate development and disease has expanded
dramatically over the past decade. While many articles have discussed the strengths of …

Practical application of ontologies to annotate and analyse large scale raw mouse phenotype data

T Beck, H Morgan, A Blake, S Wells, JM Hancock… - BMC …, 2009 - Springer
Background Large-scale international projects are underway to generate collections of
knockout mouse mutants and subsequently to perform high throughput phenotype …

Isolation of Novel CreERT2-Driver Lines in Zebrafish Using an Unbiased Gene Trap Approach

P Jungke, J Hammer, S Hans, M Brand - PloS one, 2015 - journals.plos.org
Gene manipulation using the Cre/loxP-recombinase system has been successfully
employed in zebrafish to study gene functions and lineage relationships. Recently, gene …

New mutant phenotype data curation system in the Saccharomyces Genome Database

MC Costanzo, MS Skrzypek, R Nash… - … : The Journal of …, 2009 - academic.oup.com
Abstract The Saccharomyces Genome Database (SGD; http://www. yeastgenome. org/)
organizes and displays molecular and genetic information about the genes and proteins of …