Although many agents have therapeutic potentials for central nervous system (CNS)
diseases, few of these agents have been clinically used because of the brain barriers. As the …

Traditionally, surgery has been the only cure for many solid tumours. Technological
advances have catalysed a shift from open surgery towards less invasive techniques …

Ultrasound has received widespread attention as an emerging technology for targeted, non-
invasive neuromodulation based on its ability to evoke electrophysiological and motor …

Ultrasound-induced neurostimulation has recently gained increasing attention, but little is
known about the mechanisms by which it affects neural activity or about the range of …

The feasibility of blood-brain barrier (BBB) opening in the hippocampus of wild-type mice
using focused ultrasound (FUS) through the intact skull and skin was investigated. Needle …

For medical applications of ultrasound inside the brain, it is necessary to understand the
relationship between the apparent density of skull bone and its corresponding speed of …

An ultrasound sparse array consists of a sparse distribution of elements over a 2-D aperture.
Such an array is typically characterized by a limited number of elements, which in most …

The development of multi-element arrays for better control of the shape of ultrasonic beams
has opened the way for focusing through highly aberrating media, such as the human skull …

Background: High intensity focused ultrasound (HIFU) is a noninvasive treatment modality
that induces complete coagulative necrosis of a deep tumor through the intact skin. The …

High intensity focused ultrasound (HIFU) is rapidly gaining clinical acceptance as a
technique capable of providing non-invasive heating and ablation for a wide range of …