Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that
regulates various biological processes, including proliferation, metastasis, angiogenesis …

Transcription factors are involved in a large number of human diseases such as cancers for
which they account for about 20% of all oncogenes identified so far. For long time, with the …

Curcumin is a pharmacologically active polyphenol derived from the popular spice element-
Turmeric. The therapeutic activity of curcumin has been extensively investigated over the …

Transcription factors are proteins able to bind DNA and induce the transcription of specific
genes. Consequently, they play a pivotal role in multiple cellular pathways and are …

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in signal
transmission from the plasma membrane to the nucleus, regulating the expression of genes …

Background: Since Signal Transducer and Activator of Transcription 3 (STAT3) is a
transcription factor which plays an important role in multiple aspects of cancer, including …

Cancer is one of the leading causes of mortality and morbidity worldwide, affecting millions
of people physically and financially every year. Over time, many anticancer treatments have …

Two optically pure chiral binuclear copper (II) complexes [Cu2 (μ-Cl) 2L2]· CH2Cl2 (1) and
Cu2L4 (2) based on the natural product rosin derivative N-(5-dehydroabietyl-1, 3, 4 …

The mechanisms behind the anticancer benefits of curcumin are yet unclear. It is generally
known that curcumin promotes DNA demethylation and apoptotic mechanisms and alters …

信号转导与转录激活因子3 (Signal transducer and activator of transcription 3, STAT3)
是一种在细胞中参与大量细胞因子及生长因子应答的信号转导蛋白, 负责调控细胞的生长, 增殖 …